Aslam Hira, Kamal Anam, Khan Ali Nauman, Chaudhary Ahmed Jamal, Ismail Rana
Internal Medicine, DMC Sinai-Grace Hospital, Detroit, MI, USA.
Hematology/Oncology, Ascension Providence Cancer Center, Southfield, MI, USA.
Eur J Case Rep Intern Med. 2022 Sep 19;9(9):003295. doi: 10.12890/2022_003295. eCollection 2022.
Lymphangiomas are rare, congenital malformations arising from lymphatic hyperplasia. More than 90% of cases are found in children under 2 years of age. Cystic lymphangiomas usually occur in the neck and axillary region and only rarely extend to the mediastinum.
We present the case of a middle-aged woman who presented with dyspnoea and productive cough. A chest x-ray showed right lower medial lung opacity, and a CT scan of the thorax showed a cystic mediastinal mass, encroaching on the superior vena cava and approaching the trachea and mainstem bronchus. An anterior thoracotomy with tumour resection was performed to relieve compression symptoms. The final pathology report confirmed the diagnosis of mediastinal lymphangioma.
Lymphangioma should be considered as one of the differential diagnoses when mediastinal widening is found on chest x-ray, and it should be investigated further with a CT scan and biopsy. Infiltration of surrounding structures can cause compression symptoms and can also make surgical resection more challenging.
Lymphangiomas are benign tumours of the paediatric population that can rarely occur in middle-aged adults as an acquired form.It is essential to investigate mediastinal enlargement seen on chest x-ray images even in the absence of any symptoms, as mediastinal lymphangiomas can grow to involve nearby anatomical structures.Although benign, lymphangiomas should be excised at the time of diagnosis to avoid anticipated complications and compression of anatomical structures causing respiratory difficulty, hoarseness and superior vena cava syndrome.Complete surgical resection is the mainstay of treatment and provides an excellent postoperative prognosis.
淋巴管瘤是一种罕见的先天性畸形,由淋巴组织增生引起。超过90%的病例见于2岁以下儿童。囊性淋巴管瘤通常发生在颈部和腋窝区域,很少延伸至纵隔。
我们报告一例中年女性,表现为呼吸困难和咳痰。胸部X线显示右下肺内侧模糊影,胸部CT扫描显示纵隔囊性肿块,侵犯上腔静脉并靠近气管和主支气管。行前开胸肿瘤切除术以缓解压迫症状。最终病理报告确诊为纵隔淋巴管瘤。
当胸部X线发现纵隔增宽时,应将淋巴管瘤列为鉴别诊断之一,并进一步行CT扫描和活检。周围结构受侵可导致压迫症状,也会使手术切除更具挑战性。
淋巴管瘤是儿科常见的良性肿瘤,极少以后天获得性形式发生于中年成年人。即使没有任何症状,对胸部X线图像上显示的纵隔增大进行检查也很重要,因为纵隔淋巴管瘤可生长并累及附近解剖结构。尽管淋巴管瘤是良性的,但在诊断时应予以切除,以避免预期的并发症以及解剖结构受压导致的呼吸困难、声音嘶哑和上腔静脉综合征。完整的手术切除是主要治疗方法,术后预后良好。