Altuwaijri Fawaz, Amshan Karam, Alanazi Amani Y, Alanazi Dalal F, Alghofili Hesham, Altuwaijri Mansour, Altuwaijri Talal, Altoijry Abdulmajeed
Department of Emergency Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Division of Vascular Surgery, Department of Surgery, College of Medicine, King Saud University, Riyadh, SAU.
Cureus. 2022 Sep 23;14(9):e29513. doi: 10.7759/cureus.29513. eCollection 2022 Sep.
There are limited data regarding potential triggering factors of pulmonary embolism (PE) in coronavirus disease 2019 (COVID-19) patients and its outcomes in comparison with non-infected PE patients. We aimed to identify the contribution of COVID-19 among patients diagnosed with PE and compare risk factors, laboratory results, and outcomes between COVID-19 PE patients and non-COVID-19 PE patients.
This was a retrospective study of all PE patients between March 2020 and December 2020. The patients were segmented into two groups based on a COVID-19 nasopharyngeal swab result. Statistical analysis was used to determine the differences in risk factors, laboratory values, and outcomes.
A total of 58 patients were included. Females comprised 44.8% of the total sample. Overall, 16 patients (27.6%) were COVID-19 positive. Being non-Saudi was observed more in PE COVID-19 patients compared with non-COVID-19 patients (43.7% vs 4.8%, P = 0.001). Intensive care unit (ICU) admission occurred in 50% of COVID-19 PE patients.
COVID-19 was associated with 27.6% of the PEs in our hospital. Being male or a foreign resident was observed to be associated with COVID-19 PE. Further studies with larger sample sizes are needed, but these results may help the medical community regarding the increased risk of PE among COVID-19 patients and provide evidence of some potentially predictive factors that can be used to identify COVID-19 in high-risk patients.
关于2019冠状病毒病（COVID-19）患者肺栓塞（PE）的潜在触发因素及其与未感染PE患者相比的结果的数据有限。我们旨在确定COVID-19在诊断为PE的患者中的作用，并比较COVID-19 PE患者和非COVID-19 PE患者的危险因素、实验室检查结果及预后。
这是一项对2020年3月至2020年12月期间所有PE患者的回顾性研究。根据COVID-19鼻咽拭子检测结果将患者分为两组。采用统计分析来确定危险因素、实验室值和预后的差异。
共纳入58例患者。女性占总样本的44.8%。总体而言，16例患者（27.6%）COVID-19呈阳性。与非COVID-19患者相比，COVID-19 PE患者中非沙特人更为常见（43.7%对4.8%，P = 0.001）。50%的COVID-19 PE患者入住了重症监护病房（ICU）。
在我院，27.6%的PE与COVID-19有关。男性或外国居民被认为与COVID-19 PE有关。需要进行更大样本量的进一步研究，但这些结果可能有助于医学界了解COVID-19患者中PE风险增加的情况，并提供一些潜在预测因素的证据，可用于识别高危患者中的COVID-19。
