Venero Hidalgo Lidia, Vázquez-Martínez Andrea, Aliño Marta, Cano-López Irene, Villanueva-Blasco Víctor José
Facultad de Ciencias de la Salud, Universidad Internacional de Valencia. Valencia. España.
Grupo de Investigación en Salud y Ajuste Psico-Social (GI-SAPS), Universidad Internacional de Valencia. Valencia. España.
Rev Esp Salud Publica. 2022 Oct 27;96:e202210082.
Cannabis is an illegal drug whose use has increased in recent years, especially among adolescents. Despite its popularity, its use and abuse brings with it health consequences, being greater if consumption occurs in the adolescent stage, since the brain is in full development. The objective of this systematic review was to determine the effects of cannabis use on cognitive functions of attention and memory in adolescent population.
A systematic review of the literature was carried out in the main search portals (Pubmed, Web of Science, SciELO, Cochrane) referring to the last 10 years, following the PRISMA criteria. The systematic search strategy was carried out in the period from March to May 2021, applying the PICO method and the PEDro scale to guarantee the methodological quality of the included studies.
Both attention and memory are affected by cannabis use; however, memory functions improve with abstinence, not being so for attention. Memory deficits are an indicator of therapeutic abandonment of addiction treatment. In relation to psychosocial interventions aimed at improving memory, the contingency management, educational interventions and motivational interviewing have not been shown to be effective on the effects of substances. Working memory training offers positive results, although not clinically significant. Finally, memory deficits are an indicator of therapeutic abandonment of pharmacological treatment for cannabis addiction. Therefore, research is needed aimed both at reducing the side effects of drugs on memory processes and at establishing to what extent memory deficits associated with cannabis use can facilitate therapeutic abandonment.
More research is necessary, considering the dual consumption of cannabis-tobacco and the effects that both substances may have jointly and separately on attention and memory processes.
大麻是一种非法药物,近年来其使用有所增加,尤其是在青少年中。尽管它很流行,但其使用和滥用会带来健康后果,如果在青少年阶段使用,后果会更严重,因为此时大脑正处于全面发育阶段。本系统评价的目的是确定大麻使用对青少年注意力和记忆认知功能的影响。
按照PRISMA标准,在主要搜索平台(PubMed、科学网、SciELO、Cochrane)对过去10年的文献进行系统评价。系统检索策略于2021年3月至5月期间实施,应用PICO方法和PEDro量表以确保纳入研究的方法学质量。
注意力和记忆都会受到大麻使用的影响;然而,记忆功能在戒断后会改善,注意力则不然。记忆缺陷是成瘾治疗中治疗中断的一个指标。关于旨在改善记忆的心理社会干预措施,应急管理、教育干预和动机访谈尚未显示对物质的影响有效。工作记忆训练产生了积极结果,尽管在临床上不显著。最后,记忆缺陷是大麻成瘾药物治疗中治疗中断的一个指标。因此,需要开展研究,既要减少药物对记忆过程的副作用,也要确定与大麻使用相关的记忆缺陷在多大程度上会促使治疗中断。
考虑到大麻与烟草的双重消费以及这两种物质可能对注意力和记忆过程产生的联合和单独影响,有必要进行更多研究。