使用人羊膜治疗复发性高度近视黄斑裂孔伴视网膜脱离
Treatment of recurrent high myopic macular hole associated with retinal detachment using a human amniotic membrane.
作者信息
Caporossi Tomaso, Governatori Lorenzo, Gambini Gloria, Baldascino Antonio, De Vico Umberto, Ripa Matteo, Scampoli Alessandra, Carlà Matteo Mario, Rizzo Clara, Kilian Raphael, Rizzo Stanislao
机构信息
Ophthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Catholic University Sacro Cuore, Rome, Italy.
出版信息
Jpn J Ophthalmol. 2022 Nov;66(6):518-526. doi: 10.1007/s10384-022-00953-w. Epub 2022 Oct 27.
PURPOSE
To determine the efficacy of using a human amniotic membrane to close macular hole retinal detachment in highly myopic eyes.
STUDY DESIGN
Prospective, consecutive, nonrandomized interventional study.
METHODS
We included 19 high myopic eyes from 19 patients affected by macular hole retinal detachment who had already undergone vitrectomy with internal limiting membrane peeling. The patients underwent vitrectomy with amniotic membrane transplant.
RESULTS
Primary success was achieved after 3 months in 89.5% (17 of 19 eyes) and final macular hole closure was obtained in 94.7% (18 of 19 eyes) of the patients. The final retinal reattachment rate was 100%. The final 12-month mean BCVA improved from 20/2000 (2 logMAR) to 20/250 (1.1 logMAR). OCT-angiography revealed a high correlation between the superficial and deep capillary plexus and the final BCVA.
CONCLUSION
Human amniotic membrane patches can effectively repair macular hole retinal detachment in high myopic eyes in terms of anatomic results and BCVA recovery.
目的
确定使用人羊膜封闭高度近视眼中黄斑裂孔性视网膜脱离的疗效。
研究设计
前瞻性、连续性、非随机干预性研究。
方法
我们纳入了19例患有黄斑裂孔性视网膜脱离的患者的19只高度近视眼，这些患者已经接受了玻璃体切除术并剥除了内界膜。患者接受了羊膜移植玻璃体切除术。
结果
3个月后，89.5%（19只眼中的17只）取得了初步成功，94.7%（19只眼中的18只）的患者最终实现了黄斑裂孔闭合。最终视网膜复位率为100%。最终12个月时，平均最佳矫正视力从20/2000（2 logMAR）提高到20/250（1.1 logMAR）。光学相干断层扫描血管造影显示，浅表和深部毛细血管丛与最终最佳矫正视力之间存在高度相关性。
结论
就解剖学结果和最佳矫正视力恢复而言，人羊膜片可有效修复高度近视眼中的黄斑裂孔性视网膜脱离。
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