Department of Chemistry, Kamil Ozdag Science Faculty, Karamanoglu Mehmetbey University, 70100 Karaman, Turkey.
Department of Chemistry, Kamil Ozdag Science Faculty, Karamanoglu Mehmetbey University, 70100 Karaman, Turkey; Department of Analytical Chemistry, Faculty of Pharmacy, Istanbul University-Cerrahpaşa, 34500 Istanbul, Turkey.
Food Chem. 2023 Feb 15;402:134439. doi: 10.1016/j.foodchem.2022.134439. Epub 2022 Sep 29.
A new cyanobiphenyl-based compound 4-hydroxy-3-(((4-(phenylamino)phenyl)imino)methyl)-[1,1-biphenyl]-4-carbonitrile (PEBP) for Cu detection was fabricated and successfully characterized. PEBP was employed as a sensor for Cu sensing and used as an extremely fast responsive colorimetric and ''ON/OFF'' fluorescent sensor in HO:CHCN (40:60, v/v). Highly selective fluorescence response of PEBP to Cu yielded an excellently low detection limit of 20.4 nM. Binding stoichiometry for PEBP-Cu was found to be 2:1 by Job's plot study, as well MALDI TOF-MS data, and the binding constant was computed as 0.62 × 10 M. The validation study was employed using analytical parameters and statistical tests. To understand the binding capability, density functional theory (DFT) study was performed. Smartphone and applications for different food and drinking water samples were successfully constructed for Cu detection, and the findings revealed that PEBP could be easily employed for in-site Cudetection without sophisticated instrument.
一种新的基于氰基联苯的化合物 4-羟基-3-(((4-(苯氨基)苯基)亚氨基)甲基)-[1,1-联苯]-4-甲腈 (PEBP) 被制造出来，并成功地进行了表征。PEBP 被用作 Cu 检测的传感器，并在 HO:CHCN（40:60，v/v）中用作极快速响应的比色和“开/关”荧光传感器。PEBP 对 Cu 具有高度选择性的荧光响应，产生了出色的低检测限 20.4 nM。通过 Job 图研究、MALDI TOF-MS 数据以及结合常数计算为 0.62×10 M，发现 PEBP-Cu 的结合比为 2:1。使用分析参数和统计测试进行了验证研究。为了了解结合能力，进行了密度泛函理论 (DFT) 研究。成功构建了用于不同食品和饮用水样本的 Cu 检测智能手机和应用程序，研究结果表明，PEBP 无需复杂仪器即可轻松用于现场 Cu 检测。
