Tekneci Ahmet Kayahan, Akçam Tevfik İlker, Kavurmacı Önder, Ergönül Ayşe Gül, Özdil Ali, Turhan Kutsal, Çakan Alpaslan, Çağırıcı Ufuk
Department of Thoracic Surgery, Ege University School of Medicine, Izmir, Türkiye.
Department of Thoracic Surgery, University of Health Sciences, Bozyaka Izmir Training and Research Hospital, Izmir, Türkiye.
Turk Gogus Kalp Damar Cerrahisi Derg. 2022 Jul 29;30(3):381-388. doi: 10.5606/tgkdc.dergisi.2022.21217. eCollection 2022 Jul.
This study aims to investigate the relationship between preoperative erythrocyte sedimentation rate and survival in patients undergoing pulmonary resection due to lung cancer.
Between January 2011 and July 2017, a total of 575 patients (433 males, 142 females; mean age: 61.2±9.9 years; range, 29 to 82 years) who were operated due to primary lung cancer in our clinic were retrospectively analyzed. The patients were grouped according to erythrocyte sedimentation rate to analyze the relationship between erythrocyte sedimentation rate and survival.
The mean overall survival time was 61.8±1.7 months in 393 patients with an erythrocyte sedimentation rate of ≤24 mm/h and 48.9±2.9 months in 182 patients with an erythrocyte sedimentation rate of ≥25 mm/h (p<0.001). Among the patients with Stage 1-2 disease, the mean survival time was 66.2±1.9 in patients with an erythrocyte sedimentation rate of ≤24 mm/h and 53.8±3.2 in patients with an erythrocyte sedimentation rate of ≥25 mm/h (p=0.008). The mean survival time in patients with adenocarcinoma was 62.4±2.4 months in patients with ≤24 mm/h erythrocyte sedimentation rate and 46.1±4.6 months in patients with ≥25 mm/h erythrocyte sedimentation rate (p=0.003).
The relationship between elevated erythrocyte sedimentation rate and poor prognosis in patients with the same stage of the disease is promising for the use of erythrocyte sedimentation rate as a prognostic marker.
本研究旨在调查因肺癌接受肺切除术患者术前红细胞沉降率与生存率之间的关系。
回顾性分析2011年1月至2017年7月期间在我院因原发性肺癌接受手术的575例患者（男性433例，女性142例；平均年龄：61.2±9.9岁；范围29至82岁）。根据红细胞沉降率对患者进行分组，以分析红细胞沉降率与生存率之间的关系。
红细胞沉降率≤24 mm/h的393例患者的平均总生存时间为61.8±1.7个月，红细胞沉降率≥25 mm/h的182例患者的平均总生存时间为48.9±2.9个月（p<0.001）。在1-2期疾病患者中，红细胞沉降率≤24 mm/h的患者平均生存时间为66.2±1.9个月，红细胞沉降率≥25 mm/h的患者平均生存时间为53.8±3.2个月（p=0.008）。腺癌患者中，红细胞沉降率≤24 mm/h的患者平均生存时间为62.4±2.4个月，红细胞沉降率≥25 mm/h的患者平均生存时间为46.1±4.6个月（p=0.003）。
疾病处于同一阶段的患者中，红细胞沉降率升高与预后不良之间的关系表明红细胞沉降率有望作为一种预后标志物。
