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红细胞沉降率作为冠心病的一个标志物。

Erythrocyte sedimentation rate as a marker for coronary heart disease.

作者信息

Yayan Josef

机构信息

Department of Internal Medicine, Vinzentius Hospital, Landau, Germany.

出版信息

Vasc Health Risk Manag. 2012;8:219-23. doi: 10.2147/VHRM.S29284. Epub 2012 Apr 11.

DOI:10.2147/VHRM.S29284
PMID:22536077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3333472/
Abstract

BACKGROUND

Patients with angina pectoris or myocardial infarction frequently present without evidence of cardiac-specific heart enzymes by laboratory analysis or specific pathologic electro-cardiogram findings. The current study analyzed the efficacy of the erythrocyte sedimentation rate as an additional potential indicator for coronary heart disease, the aim being to enable quicker identification of patients with angina pectoris or myocardial infarction so that they can be more rapidly treated.

METHODS

Patients with angina pectoris or myocardial infarction who had undergone a heart catheter examination were included in the study. The diagnosis of acute coronary heart disease was made by the physician who performed coronary angiography. Patients without coronary heart disease were used as a control group. The erythrocyte sedimentation rate was measured in all patients. Patients with angina pectoris or myocardial infarction and an inflammatory or tumor disease were excluded.

RESULTS

The erythrocyte sedimentation rate was prolonged in 79 (58.09%) of 136 patients; 69 (50.74%) patients (95% confidence interval ±8.4%, 42.34%-59.14%) had coronary heart disease and a prolonged erythrocyte sedimentation rate. The erythrocyte sedimentation rate was prolonged in ten (7.35%) patients (95% confidence interval ±4.39%, 2.96%-11.74%) without coronary heart disease by coronary angiography. The specificity of the erythrocyte sedimentation rate for coronary heart disease was 70.59% and the sensitivity was 67.65%.

CONCLUSION

Erythrocyte sedimentation rate may be a useful additional diagnostic criterion for coronary heart disease.

摘要

背景

心绞痛或心肌梗死患者经实验室分析或特异性病理心电图检查，常无心脏特异性心肌酶证据。本研究分析红细胞沉降率作为冠心病另一潜在指标的有效性，目的是能更快识别心绞痛或心肌梗死患者，以便更迅速地进行治疗。

方法

纳入已接受心脏导管检查的心绞痛或心肌梗死患者。由进行冠状动脉造影的医生做出急性冠心病诊断。无冠心病患者作为对照组。测量所有患者的红细胞沉降率。排除患有心绞痛或心肌梗死且合并炎症或肿瘤疾病的患者。

结果

136例患者中有79例（58.09%）红细胞沉降率延长；69例（50.74%）患者（95%置信区间±8.4%，42.34%-59.14%）患有冠心病且红细胞沉降率延长。冠状动脉造影显示无冠心病的患者中有10例（7.35%）（95%置信区间±4.39%，2.96%-11.74%）红细胞沉降率延长。红细胞沉降率对冠心病的特异性为70.59%，敏感性为67.65%。

结论

红细胞沉降率可能是冠心病一个有用的辅助诊断标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/ba58a0478a2b/vhrm-8-219f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/b73b1362a257/vhrm-8-219f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/e8f27311ff71/vhrm-8-219f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/9b543419bcb4/vhrm-8-219f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/ba58a0478a2b/vhrm-8-219f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/b73b1362a257/vhrm-8-219f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/e8f27311ff71/vhrm-8-219f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/9b543419bcb4/vhrm-8-219f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b1/3333472/ba58a0478a2b/vhrm-8-219f4.jpg

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