Horio T, Murai T, Ikai K
Arch Dermatol. 1978 Oct;114(10):1498-500.
A photosensitive lichen planus-like eruption developed in a 63-year-old man during postoperative chemotherapy with 1-(2-tetrahydrofuryl)-5-fluorouracil. The action spectrum for the photosensitivity was in the long-wave ultraviolet light (UV-A). The reaction was reproducible on readministration of the drug and exposure to UV-A. At the time of this test, a flare-up phenomenon was observed at previously involved sites. The photopatch test was negative with the drug. Patients taking the drug who had no dermatitis were not sensitive to UV-A. These observations suggest that the photosensitivity that occurred in the patient was possibly photoallergic.
一名63岁男性在接受1-(2-四氢呋喃基)-5-氟尿嘧啶术后化疗期间出现了光敏性扁平苔藓样皮疹。光敏反应的作用光谱在长波紫外线（UV-A）范围内。再次给药并暴露于UV-A时，反应可重现。在此次试验时，在先前受累部位观察到了 flare-up 现象。药物光斑试验为阴性。服用该药物且无皮炎的患者对UV-A不敏感。这些观察结果表明，该患者发生的光敏性可能是光变应性的。
