Bouvier M, Zimny M L
Acta Anat (Basel). 1987;129(4):293-300. doi: 10.1159/000146418.
Mechanical loads on the condylar cartilage were varied by feeding either a hard diet, a soft diet, or a sequential combination of a soft diet followed by a hard diet to young male and female rats for a total period of 4 weeks, and to mature male rats for 12 weeks. Gross condylar dimensions were greatest in the hard-diet groups, intermediate in the combination soft/hard-diet groups, and smallest in the soft-diet groups. Scanning electron microscopy of the condyle revealed a smooth, nonporous articular surface in the soft-diet groups. Hard-diet condyles had a rougher, more porous articular surface while soft/hard-diet condyles were intermediate between nonporous and slightly roughened condyles. None of the condyles showed ridges or elevations on the articular surface. Sex, age and time of the diets did not significantly affect these results.
通过分别给年轻雄性和雌性大鼠喂食硬食、软食，或先喂软食后喂硬食的顺序组合饮食，持续4周，给成年雄性大鼠喂食12周，来改变髁突软骨上的机械负荷。髁突的总体尺寸在硬食组中最大，软食/硬食组合组居中，软食组最小。髁突的扫描电子显微镜检查显示，软食组的关节表面光滑、无孔。硬食组的髁突关节表面更粗糙、孔隙更多，而软食/硬食组的髁突介于无孔和略粗糙的髁突之间。所有髁突的关节表面均未显示出嵴或隆起。性别、年龄和饮食时间对这些结果没有显著影响。
