Department of Urology, St. Vincent's University Hospital, Dublin, Ireland.
Department of Urology, Freeman Hospital, Newcastle upon Tyne, UK.
BMJ Case Rep. 2022 Oct 28;15(10):e248833. doi: 10.1136/bcr-2022-248833.
A woman in her 60s presented with a 2-week history of non-specific left-sided abdominal pain. She previously underwent a total parotidectomy and adjuvant radiotherapy for left parotid adenoid cystic carcinoma 13 years prior, with a local recurrence 4 years after. Investigations revealed a large left-sided renal mass with appearances of renal carcinoma and no signs of metastatic disease. Pathology following nephrectomy revealed a metastatic adenoid cystic carcinoma.Metastatic disease recurred 11 months postradical nephrectomy to the contralateral kidney and lung, and she was referred to medical oncology for further management.This case history demonstrates the highly aggressive nature of an adenoid cystic carcinoma primary of salivary gland origin with rare metastasis to the kidney.
一位 60 多岁的女性因左腹部非特异性疼痛 2 周就诊。她曾于 13 年前因左侧腮腺腺样囊性癌行全腮腺切除术和辅助放疗,4 年后局部复发。检查发现左侧肾有一个大肿块,表现为肾细胞癌,没有转移的迹象。肾切除术后的病理显示为转移性腺样囊性癌。根治性肾切除术后 11 个月,转移性疾病复发到对侧肾脏和肺部,她被转介到肿瘤内科进一步治疗。该病例说明了源于唾液腺的腺样囊性癌原发灶具有高度侵袭性,且罕见转移至肾脏。