Hansen K, Gjerris F, Sørensen P S
Acta Neurochir (Wien). 1987;86(3-4):93-7. doi: 10.1007/BF01402291.
Four patients are described presenting papilloedema, increased pressure and reduced CSF absorption--caused by either spinal tumours, leptomeningeal carcinomatosis or encephalitis. Remarkably they all had a normal CT without signs of hydrocephalus. A 24-hour intracranial pressure monitoring showed a mean pressure of 30-35 mm Hg, recurrent plateau waves and high occurrence of B waves. Conductance to CSF outflow studied by a constant perfusion test was severely reduced 0.010-0.026 ml min-1 mm Hg-1 (normal greater than 0.12 ml mm Hg-1 min-1). Despite these findings no ventricular enlargement was seen on serial CT scans. The reason therefore remains unknown. Disappearance of papilloedema and a variable clinical improvement followed shunt-insertion.
本文描述了4例出现视乳头水肿、颅内压升高和脑脊液吸收减少的患者，病因分别为脊髓肿瘤、软脑膜癌病或脑炎。值得注意的是，他们的CT检查均正常，无脑积水迹象。24小时颅内压监测显示平均压力为30 - 35 mmHg，反复出现平台波，B波发生率高。通过恒定灌注试验研究的脑脊液流出传导率严重降低，为0.010 - 0.026 ml·min⁻¹·mmHg⁻¹（正常大于0.12 ml·mmHg⁻¹·min⁻¹）。尽管有这些发现，但系列CT扫描未发现脑室扩大。其原因尚不清楚。分流术后视乳头水肿消失，临床症状有不同程度改善。
