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一例足部皮肤结核的有趣病例报告。

An interesting case report of cutaneous tuberculosis of the foot.

作者信息

Tharun Ganapathy C, George Nidhi Mariam, Selvamuthukumaran Sundeep, Anguraj Preetam, Gilani Amit

机构信息

Department of General Surgery, SRM Medical College Hospital and Research Centre, India.

Department of General Surgery, SRM Medical College Hospital and Research Centre, India.

出版信息

Int J Surg Case Rep. 2022 Nov;100:107763. doi: 10.1016/j.ijscr.2022.107763. Epub 2022 Oct 23.

Abstract

INTRODUCTION AND IMPORTANCE

Tuberculosis is an age old disease caused by Mycobacterium tuberculosis which has been a menace to public health and thwarting economic growth. Pulmonary tuberculosis being the most common type, extra pulmonary tuberculosis has a greater association with HIV and multidrug resistant tuberculosis. Cutaneous tuberculosis accounts for 1-1.5 % of extra pulmonary tuberculosis.

CASE PRESENTATION

A 32 year old female presented to the outpatient department with a two month history of ulcer over the sole of the foot with multiple discharging sinuses and surrounding induration. Laboratory tests reported elevated total leukocyte counts. Magnetic Resonance Imaging of the foot showed diffuse intermuscular edema with an interconnecting sinus tract draining to the sole of the foot. Regular wound dressings and antibiotics showed no resolution. Patient eventually underwent near complete excision of the ulcer. The biopsy was suggestive of tuberculous etiology. She achieved complete resolution with antituberculous drugs by three months.

CLINICAL DISCUSSION

Cutaneous tuberculosis is often misdiagnosed as it can masquerade as many other commonly encountered dermatological conditions. Microbiological diagnosis plays a crucial role in the accurate diagnosis of cutaneous tuberculosis. These lesions are highly responsive to antituberculous drugs.

CONCLUSION

Cutaneous tuberculosis is a rare disease that should be considered in the differential diagnosis of patients with chronic non-healing wounds that are poorly responsive to conventional treatment methods.

摘要

引言与重要性

结核病是一种由结核分枝杆菌引起的古老疾病,一直对公共卫生构成威胁并阻碍经济增长。肺结核是最常见的类型,肺外结核与艾滋病毒和耐多药结核病的关联更大。皮肤结核占肺外结核的1 - 1.5%。

病例介绍

一名32岁女性到门诊就诊,有两个月的足底溃疡病史,伴有多个排脓窦道和周围硬结。实验室检查报告白细胞总数升高。足部磁共振成像显示弥漫性肌间水肿,有一个相互连通的窦道引流至足底。常规伤口敷料和抗生素治疗无效。患者最终接受了溃疡的近乎完全切除。活检提示为结核病因。三个月后,她通过抗结核药物治疗实现了完全康复。

临床讨论

皮肤结核常被误诊,因为它可能伪装成许多其他常见的皮肤病。微生物学诊断在皮肤结核的准确诊断中起着关键作用。这些病变对抗结核药物高度敏感。

结论

皮肤结核是一种罕见疾病,在对传统治疗方法反应不佳的慢性不愈合伤口患者的鉴别诊断中应予以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8767/9618970/c0b07c9c746f/gr1.jpg

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