Ro J Y, Ayala A G, el-Naggar A
Am J Surg Pathol. 1987 Sep;11(9):668-73. doi: 10.1097/00000478-198709000-00002.
We report the results of a histologic evaluation of muscle (muscularis mucosa) in the lamina propria of the urinary bladder performed on 100 consecutive cystectomy specimens. Muscle fibers were found in the lamina propria lying parallel to the mucosa and forming a distinct muscularis mucosa in three cases; they were interrupted or discontinuous in 20 cases, and dispersed or scattered, forming thin bundles, in 71 cases. In six cases, there were no muscle fibers in the lamina propria. In addition, we noticed that the lamina propria contains large vessels that run along the length of the lamina propria in a continuous or interrupted fashion. When muscle fibers are present, they are associated with these vessels. Since prognosis and management of muscle invasive carcinomas (stage B) is different from that of lamina propria-invasive tumors (stage A), pathologists and urologists should be aware of the presence of a muscularis mucosa in the urinary bladder.
我们报告了对100例连续膀胱切除标本的膀胱固有层内肌肉（黏膜肌层）进行组织学评估的结果。在固有层中发现肌纤维与黏膜平行排列，在3例中形成了明显的黏膜肌层；在20例中肌纤维中断或不连续，在71例中分散或呈散在分布，形成细束状。在6例中，固有层内没有肌纤维。此外，我们注意到固有层含有沿固有层长度呈连续或间断走行的大血管。当存在肌纤维时，它们与这些血管相关。由于肌层浸润性癌（B期）的预后和治疗与固有层浸润性肿瘤（A期）不同，病理学家和泌尿科医生应注意膀胱中黏膜肌层的存在。
