后牙区功能性牙数与血清 uCOC 水平的相关性。

Functional tooth number in the posterior region associated serum ucOC levels.

机构信息

Division of Oral Reconstruction and Rehabilitation, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-Ku, Kitakyushu, Fukuoka, 803-8580, Japan.

Department of Maxillofacial Implant, Asahi University School of Dentistry, Mizuho, Japan.

出版信息

Int J Implant Dent. 2022 Nov 1;8(1):50. doi: 10.1186/s40729-022-00450-2.

DOI:10.1186/s40729-022-00450-2

PMID:36316516

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9622957/

Abstract

PURPOSE

The purpose of this study was to investigate serum undercarboxylated osteocalcin (ucOC) levels in partially edentulous patients scheduled to receive implant treatment and determine the association between ucOC levels, vegetable intake, vitamin K, dietary fiber intake, and functional tooth number in the posterior region (p-FTN).

METHODS

A total of 46 patients (20 male and 26 female, 61.9 ± 12.7 years old) were included. The association among serum ucOC levels, vegetable intake, vitamin K and dietary fiber intake was assessed using Spearman's rank correlation coefficient and binary logistic regression analysis.

RESULTS

In total, 35% of patients (16/46 subjects) showed an abnormally high ucOC level (≧ 4.5 ng/mL). p-FTN showed a weak positive correlation with vegetable intake, vitamin K and dietary fiber intake (r = 0.28, 0.21, and 0.14, respectively) and a significant negative correlation with ucOC levels (r = - 0.51). Multivariate analysis demonstrated that p-FTN as well as vitamin K intake showed a significant negative association with serum ucOC levels.

CONCLUSIONS

More than one-third of patients showed abnormally high ucOC levels. p-FTN showed a negative association with serum ucOC levels, which indicated the possibility that oral status affected bone quality.

摘要

目的

本研究旨在调查计划接受种植治疗的部分无牙患者的血清低羧化骨钙素（ucOC）水平，并确定 ucOC 水平、蔬菜摄入量、维生素 K、膳食纤维摄入量与后牙区功能性牙数（p-FTN）之间的关系。

方法

共纳入 46 名患者（男 20 名，女 26 名，年龄 61.9±12.7 岁）。采用 Spearman 秩相关系数和二项逻辑回归分析评估血清 ucOC 水平、蔬菜摄入量、维生素 K 和膳食纤维摄入量之间的相关性。

结果

共有 35%（16/46 例）的患者表现出异常高的 ucOC 水平（≧4.5ng/mL）。p-FTN 与蔬菜摄入量、维生素 K 和膳食纤维摄入量呈弱正相关（r=0.28、0.21 和 0.14），与 ucOC 水平呈显著负相关（r=-0.51）。多变量分析表明，p-FTN 和维生素 K 摄入量与血清 ucOC 水平呈显著负相关。