Akron Children's Hospital, One Perkins Square, Akron, OH, USA.
University of Nebraska Medical Center, Omaha, NE, USA.
BMC Infect Dis. 2022 Oct 31;22(1):811. doi: 10.1186/s12879-022-07789-2.
The Meningitis/Encephalitis FilmArray® Panel (ME panel) was approved by the U.S. Food and Drug Administration in 2015 and provides rapid results when assessing patients with suspected meningitis or encephalitis. These patients are evaluated by various subspecialties including pediatric hospital medicine (PHM), pediatric emergency medicine (PEM), pediatric infectious diseases, and pediatric intensive care unit (PICU) physicians. The objective of this study was to evaluate the current use of the ME panel and describe the provider and subspecialty practice variation.
We conducted an online cross-sectional survey via the American Academy of Pediatrics Section of Hospital Medicine (AAP-SOHM) ListServe, Brown University PEM ListServe, and PICU Virtual pediatric system (VPS) Listserve.
A total of 335 participants out of an estimated 6998 ListServe subscribers responded to the survey. 68% reported currently using the ME panel at their institutions. Among test users, most reported not having institutional guidelines on test indications (75%) or interpretation (76%). 58% of providers self-reported lack of knowledge of the test's performance characteristics. Providers from institutions that have established guidelines reported higher knowledge compared to those that did not (51% vs. 38%; p = 0.01). More PHM providers reported awareness of ME panel performance characteristics compared to PEM physicians (48% vs. 27%; p = 0.004); confidence in test interpretation was similar between both groups (72 vs. 69%; p = 0.80).
Despite the widespread use of the ME panel, few providers report having institutional guidelines on test indications or interpretation. There is an opportunity to provide knowledge and guidance about the ME panel among various pediatric subspecialties.
脑膜炎/脑炎 FilmArray® 检测 Panel（ME 检测 Panel）于 2015 年获得美国食品和药物管理局批准，用于评估疑似脑膜炎或脑炎患者时可快速得到结果。这些患者由儿科医院医学（PHM）、儿科急诊医学（PEM）、儿科传染病学和儿科重症监护病房（PICU）等各种专业的医生进行评估。本研究的目的是评估 ME 检测 Panel 的当前使用情况，并描述提供者和亚专业的实践差异。
我们通过美国儿科学会医院医学科（AAP-SOHM）列表服务、布朗大学 PEM 列表服务和 PICU 虚拟儿科系统（VPS）列表服务进行了在线横断面调查。
在估计的 6998 名列表服务订户中，共有 335 名参与者对调查做出了回应。68%的人报告其所在机构目前正在使用 ME 检测 Panel。在测试使用者中，大多数人报告称其所在机构没有关于测试适应证（75%）或解读（76%）的指南。58%的提供者自述缺乏对该测试性能特征的了解。有建立指南的机构的提供者报告的知识水平高于没有建立指南的机构（51%比 38%；p=0.01）。与 PEM 医生相比，更多的 PHM 提供者报告了解 ME 检测 Panel 的性能特征（48%比 27%；p=0.004）；两组对测试解读的信心相似（72%比 69%；p=0.80）。
尽管 ME 检测 Panel 已被广泛使用，但很少有提供者报告其所在机构有关于测试适应证或解读的指南。在各个儿科亚专业中，有机会提供关于 ME 检测 Panel 的知识和指导。
