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2011 年至 2020 年台湾麻疹和风疹的流行病学特征和危险因素。

Epidemiological features and risk factors for measles and rubella in Taiwan during 2011 to 2020.

机构信息

School of Public Health, National Defense Medical Center, Taipei City, Taiwan.

Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei City, Taiwan.

出版信息

Medicine (Baltimore). 2022 Oct 28;101(43):e31254. doi: 10.1097/MD.0000000000031254.

Abstract

The risk of geographic transmission of infectious diseases due to air travel varies greatly. Our aim is to survey empirical data that provide a retrospective historical perspective on measles and rubella. This study used the open data website provided by the Taiwan Centers for Disease Control (TCDC) to extract the reported numbers of measles and rubella case between 2011 and 2020. There were 306 cases of measles and 135 cases of rubella. The incidence of measles and rubella per million population were 0 to 6.0 and 0 to 2.6, respectively. There was a gradual increase in the numbers of cases in those aged 20-39 years, and distinct duration patterns. It indicated that the risk of contracting rubella has significantly decreased in the last 5 years. Measles cases aged 20 to 39 years accounted for 72.5% of all cases. Rubella cases aged 20 to 39 years accounted for 59.3% of all cases. The male and residency in the Taipei metropolitan area or northern area were identified as potential risk factors for measles and rubella. Coverage with the first dose of the measles, mumps and rubella (MMR) vaccine in Taiwan increased from 97.31% to 98.86%, and the uptake rate of the second dose of the MMR vaccine increased from 95.73% to 98.39% between 2010 and 2020. Furthermore, the numbers of imported cases of measles (n = 0) and rubella (n = 0) reported during the coronavirus disease 2019 (COVID-19) pandemic were lower than those from 2011 to 2019. Measles and rubella cases were imported most frequently from Cambodia and Vietnam. This study represents the first report of confirmed cases of acquired measles and rubella from surveillance data of the TCDC between 2011 and 2020, also demonstrates that the numbers of cases of measles and rubella significantly decreased in Taiwan during the COVID-19 pandemic.

摘要

由于航空旅行,传染病的地理传播风险差异很大。我们的目的是调查提供麻疹和风疹回顾性历史观点的经验数据。本研究使用台湾疾病管制署(CDC)提供的开放数据网站,提取 2011 年至 2020 年间麻疹和风疹病例的报告数量。有 306 例麻疹和 135 例风疹。每百万人麻疹和风疹的发病率分别为 0 至 6.0 和 0 至 2.6。20-39 岁人群的病例数逐渐增加,且具有明显的持续模式。这表明,在过去 5 年中,风疹感染的风险显著降低。20-39 岁的麻疹病例占所有病例的 72.5%。20-39 岁的风疹病例占所有病例的 59.3%。男性和居住地在台北都会区或北部地区被确定为麻疹和风疹的潜在危险因素。台湾麻疹、腮腺炎和风疹(MMR)疫苗的第一剂覆盖率从 97.31%增加到 98.86%,2010 年至 2020 年间,MMR 疫苗的第二剂接种率从 95.73%增加到 98.39%。此外,在 2019 年冠状病毒病(COVID-19)大流行期间,报告的麻疹(n=0)和风疹(n=0)输入病例数低于 2011 年至 2019 年的病例数。麻疹和风疹病例最常从柬埔寨和越南输入。本研究首次报告了 2011 年至 2020 年 TCDC 监测数据中确诊的获得性麻疹和风疹病例,也表明在 COVID-19 大流行期间,台湾麻疹和风疹的病例数显著减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f6/9622609/cfd8ddfb91d5/medi-101-e31254-g001.jpg

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