Cuthbert Joseph J, Pellicori Pierpaolo, Clark Andrew L
Centre for Clinical Sciences, Hull York Medical School, Kingston Upon Hull, East Riding of Yorkshire, UK.
Department of Cardiology, Hull University Teaching Hospital Trust, Kingston Upon Hull, East Riding of Yorkshire, UK.
Int J Gen Med. 2022 Oct 25;15:7961-7975. doi: 10.2147/IJGM.S295467. eCollection 2022.
Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are common causes of breathlessness which frequently co-exist; one potentially exacerbating the other. Distinguishing between the two can be challenging due to their similar symptomatology and overlapping risk factors, but a timely and correct diagnosis is potentially lifesaving. Modern treatment for HF can substantially improve symptoms and prognosis for many patients and may have beneficial effects for patients with COPD. Conversely, while many inhaled treatments for COPD can improve symptoms and reduce exacerbations, there is conflicting evidence regarding the safety of some inhaled treatments for COPD in patients with HF. Here we explore the overlap between HF and COPD, examine the effect of one condition on the other, and address the challenges of managing patients with both conditions.
心力衰竭(HF)和慢性阻塞性肺疾病(COPD)是导致呼吸急促的常见病因,且常并存;其中一种疾病可能会加重另一种疾病。由于它们症状相似且危险因素重叠,区分两者具有挑战性,但及时、正确的诊断可能挽救生命。现代HF治疗可显著改善许多患者的症状和预后,对COPD患者可能也有有益效果。相反,虽然许多COPD吸入治疗可改善症状并减少病情加重,但关于某些COPD吸入治疗对HF患者安全性的证据存在矛盾。在此,我们探讨HF和COPD之间的重叠,研究一种疾病对另一种疾病的影响,并解决同时患有这两种疾病患者的管理挑战。