From the Department of Obstetrics and Gynecology, the Arkansas Center for Birth Defects Research and Prevention, Fay W. Boozman College of Public Health, the College of Medicine, and the Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock.
South Med J. 2022 Nov;115(11):818-823. doi: 10.14423/SMJ.0000000000001471.
The objective of our study was to determine whether recommended assessments were conducted on stillbirths delivered in our predominantly rural state.
This was a descriptive study of stillbirths delivered in a rural state and included in one site of the Birth Defects Study to Evaluate Pregnancy Exposures stillbirth study. Hospital and fetal death records were examined to determine whether the following areas were evaluated: genetic testing (noninvasive perinatal testing, quad screen, amniocentesis/chorionic villus sampling with karyotype, microarrays, fetal tissue specimen), placenta/membrane/cord sent for pathologic examination, examination of the stillbirth after delivery by the healthcare provider, and fetal autopsy was performed.
From July 1, 2015 to June 30, 2020, there were 1108 stillbirths delivered in Arkansas. The most frequent assessments undertaken were placental pathology (72%), genetic testing (67%), fetal inspection (31%), and autopsy (13%). All four assessments were done in 2% of stillbirth cases, three assessments in 27%, two assessments in 47%, one assessment in 14%, and no assessment in 15%. There was no association between stillbirth assessment evaluation by gestational age (<28 weeks and > 28 weeks; 0.221); however, there was an overall association between hospital delivery volume with number of components completed ( 0.0001). Hospitals with >2000 deliveries had a higher proportion of three or four completions compared with those hospitals with <1000 deliveries or 1000 to 2000 deliveries ( 0.021 and < 0.0001).
Fetal stillbirth assessment is suboptimal in our rural state, with 15% of stillbirths having no assessment and only 2% having all four assessments. There is no association between stillbirth assessment and gestational age (<28 weeks vs >28 weeks), but there is a correlation between delivery volume and stillbirth assessment.
本研究旨在确定在我们这个以农村为主的州,是否对死产进行了推荐的评估。
这是一项对在农村州分娩的死产进行的描述性研究,包括在一个地点的出生缺陷研究,以评估妊娠暴露死产研究。检查医院和胎儿死亡记录,以确定是否评估了以下领域:遗传测试(非侵入性围产期测试、四屏测试、羊膜腔穿刺术/绒毛膜取样进行核型分析、微阵列、胎儿组织标本)、胎盘/膜/脐带送病理检查、医疗服务提供者对分娩后死产的检查,以及进行胎儿尸检。
从 2015 年 7 月 1 日至 2020 年 6 月 30 日,阿肯色州共有 1108 例死产。最常进行的评估是胎盘病理学(72%)、遗传测试(67%)、胎儿检查(31%)和尸检(13%)。所有四项评估都在 2%的死产病例中进行,三项评估在 27%的病例中进行,两项评估在 47%的病例中进行,一项评估在 14%的病例中进行,15%的病例没有评估。胎死宫内评估与胎龄(<28 周和>28 周)之间无关联(0.221);然而,医院分娩量与完成的评估数量之间存在总体关联(0.0001)。分娩量超过 2000 例的医院与分娩量低于 1000 例或 1000 至 2000 例的医院相比,完成三项或四项评估的比例更高(0.021 和<0.0001)。
在我们这个农村州,胎儿死产评估不理想,15%的死产没有评估,只有 2%的死产进行了四项评估。胎死宫内评估与胎龄(<28 周与>28 周)之间无关联,但与分娩量存在相关性。