Aftab Ghazal, Arfaee Farnoosh, Akhtardanesh Baharak, Nikbakht Brojeni Gholamreza
Department of Clinical Sciences, Faculty of Specialized Veterinary Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
Vet Res Forum. 2022 Sep;13(3):447-450. doi: 10.30466/vrf.2020.128667.2975. Epub 2022 Sep 15.
Kobuviruses are viral pathogens with broad host range presented in human gastroenteritis cases; but, the pathogenesis of these viruses in companion animals is not well described. In the present study, the presence of canine (CaKVs) and feline kobuviruses (FeKVs) was detected in the 100 fecal samples of diarrhoeic and healthy companion dogs and cats by polymerase chain reaction in Tehran, Iran. The prevalence of infection was estimated as 8.00% and 4.00% in dogs and cats, respectively. All positive samples were belonged to non-diarrhoeic animals except for a feline sample being co-infected with panleukopenia. Sequence analysis showed multiple point mutations in canine and feline Iranian strains and new feline strain was detected in the present study. This is the first detection of CaKVs and FeKVs in Iran; but, the exact role of these enteric viral pathogens and their zoonotic risks are better to be clarified in all endemic regions.
杯状病毒是在人类胃肠炎病例中出现的具有广泛宿主范围的病毒病原体；但是，这些病毒在伴侣动物中的发病机制尚未得到充分描述。在本研究中，通过聚合酶链反应在伊朗德黑兰对100份腹泻和健康伴侣犬猫的粪便样本进行检测，以确定犬杯状病毒（CaKVs）和猫杯状病毒（FeKVs）的存在情况。犬和猫的感染率分别估计为8.00%和4.00%。除一份与猫泛白细胞减少症共同感染的猫样本外，所有阳性样本均来自无腹泻的动物。序列分析显示伊朗犬和猫毒株存在多个点突变，并且在本研究中检测到新的猫毒株。这是在伊朗首次检测到CaKVs和FeKVs；但是，在所有流行地区，这些肠道病毒病原体的确切作用及其人畜共患病风险最好予以明确。
