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猫杯状病毒的检测与基因特征分析

Detection and genetic characterization of feline kobuviruses.

作者信息

Chung Joon-Yee, Kim Seong-Hee, Kim Yeon-Hee, Lee Myoung-Heon, Lee Kyoung-Ki, Oem Jae-Ku

机构信息

Viral Disease Diagnostic Laboratory, Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency, 480 Anyang-6-Dong, Anyang, 430-824, Republic of Korea.

出版信息

Virus Genes. 2013 Dec;47(3):559-62. doi: 10.1007/s11262-013-0953-8. Epub 2013 Aug 21.

Abstract

In order to survey for feline kobuviruses infection, fecal samples (n = 39) of cats with diarrhea were collected during 2011-2012. Six (14.5%) of the fecal samples tested were positive for feline kobuviruses. The partial nucleotide sequences of feline kobuviruses based on the RNA-dependent RNA polymerase gene were compared to those of other species. Feline kobuviruses were most closely related to canine kobuvirus in terms of their amino acid and nucleotide levels. In a phylogenetic tree, feline kobuviruses were also closely clustered with canine kobuvirus, Aichi virus (human), and mouse kobuvirus. This is the first report of the detection and genetic characterization of feline kobuviruses.

摘要

为了调查猫杯状病毒感染情况,在2011年至2012年期间收集了39份腹泻猫的粪便样本。检测的粪便样本中有6份(14.5%)猫杯状病毒呈阳性。基于RNA依赖性RNA聚合酶基因的猫杯状病毒部分核苷酸序列与其他物种的序列进行了比较。在氨基酸和核苷酸水平上,猫杯状病毒与犬杯状病毒关系最为密切。在系统发育树中,猫杯状病毒也与犬杯状病毒、爱知病毒(人类)和小鼠杯状病毒紧密聚类。这是关于猫杯状病毒检测和基因特征的首次报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da8e/7088707/400c86c6f77c/11262_2013_953_Fig1_HTML.jpg

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