Kamarli Altun Hulya, Suna Gulen
Department of Nutrition and Dietetics, Akdeniz University, Faculty of Health Sciences, Antalya, TUR.
Cureus. 2022 Oct 27;14(10):e30750. doi: 10.7759/cureus.30750. eCollection 2022 Oct.
Background Obesity is one of the leading risk factors for developing type 2 diabetes mellitus (T2DM). Body mass index (BMI), waist circumference, and waist/hip ratio are anthropometric measurements used to diagnose obesity. In recent years, neck circumference, one of the anthropometric indicators used in assessing obesity, has come to the fore. This study investigates the relationship between neck circumference and other anthropometric measurements and specific biochemical parameters in T2DM. Methods Four hundred sixty-four individuals with type 2 diabetes were included in the study. Subjects' body weight, height, and other anthropometric measurements like circumferences of the waist, hip, and neck were measured. BMI, waist/hip, and waist/height ratio were calculated. The biochemical tests of the subjects in the previous month from the study were accessed from the hospital information system. The relationship between anthropometric measurements and biochemical parameters with neck circumference was evaluated. Results The mean age of the subjects was 54.6±8.51 years. 56.2% were female and 43.8% were male, and the time from T2DM diagnosis was 9.9±7.49 years. Most male subjects were overweight (49.8%), and approximately one-third of the women were first-degree obese (33.0%). Body weight, BMI, waist, hip, and neck circumferences, and waist/hip and waist/height ratios were significantly higher in both male and female subjects in the neck circumference high-risk group than those in the low-risk group (p<0.05). In terms of biochemical parameters, fasting blood glucose and HbA1c values of men with neck circumference at risk were significantly higher than those in the low-risk group. Neck circumference measurements of the participants were positively correlated with body weight (r=0.543; p<0.001), height (r=0.260; p<0.001), waist circumference (r=0.562; p<0.001), hip circumference (r=0.293; p<0.001), BMI (r=0.366; p<0.001), waist/hip ratio (r=0.428, p<0.001), and waist/height ratio (r=0.393, p<0.001). Neck circumference had a low positive correlation with fasting blood glucose (r=0.165; p<0.001), HbA1c (r=0.281; p<0.001), and triglyceride (r=0.231; p<0.001) and a negative relationship with low-density lipoprotein cholesterol (r=-0.118; p=0.001). When the relationship between neck circumference and biochemical parameters was examined, it was seen that this correlation was only in men. Conclusion Neck circumference measurement is a simple and reliable method and is not affected by external factors. It correlates with other anthropometric measurements and can be used as a good indicator of the distribution of upper subcutaneous adipose tissue in T2DM. However, more studies with larger samples are needed on this subject.
肥胖是2型糖尿病（T2DM）发病的主要危险因素之一。体重指数（BMI）、腰围和腰臀比是用于诊断肥胖的人体测量指标。近年来，颈围作为评估肥胖的人体测量指标之一，受到了关注。本研究探讨颈围与其他人体测量指标及T2DM患者特定生化参数之间的关系。
本研究纳入了464例2型糖尿病患者。测量了受试者的体重、身高以及腰围、臀围和颈围等其他人体测量指标。计算了BMI、腰臀比和腰高比。从医院信息系统获取了研究前一个月受试者的生化检测结果。评估了人体测量指标和生化参数与颈围之间的关系。
受试者的平均年龄为54.6±8.51岁。女性占56.2%，男性占43.8%，从T2DM诊断到研究的时间为9.9±7.49年。大多数男性受试者超重（49.8%），约三分之一的女性为一度肥胖（33.0%）。颈围高危组的男性和女性受试者的体重、BMI、腰围、臀围和颈围以及腰臀比和腰高比均显著高于低危组（p<0.05）。就生化参数而言，颈围处于高危水平的男性的空腹血糖和糖化血红蛋白（HbA1c）值显著高于低危组。参与者的颈围测量值与体重（r=0.543；p<0.001）、身高（r=0.260；p<0.001）、腰围（r=0.562；p<0.001）、臀围（r=0.293；p<0.001）、BMI（r=0.366；p<0.001）、腰臀比（r=0.428，p<0.001）和腰高比（r=0.393，p<0.001）呈正相关。颈围与空腹血糖（r=0.165；p<0.001）、HbA1c（r=0.281；p<0.001）和甘油三酯（r=0.231；p<0.001）呈低正相关，与低密度脂蛋白胆固醇呈负相关（r=-0.118；p=0.001）。在检查颈围与生化参数之间的关系时，发现这种相关性仅在男性中存在。
颈围测量是一种简单可靠的方法，不受外部因素影响。它与其他人体测量指标相关，可作为T2DM患者上肢皮下脂肪组织分布的良好指标。然而，关于这个主题需要更多大样本的研究。
