Camen Ioana Victoria, Manolea Maria Magdalena, Vrabie Sidonia Catalina, Sandulescu Maria Sidonia, Serbanescu Mircea Sebastian, Boldeanu Mihail Virgil, Novac Liliana, Istrate-Ofiteru Anca Maria, Neamtu Simona Daniela, Dijmarescu Anda Lorena
Ph.D. student, Doctoral School, University of Medicine and Pharmacology of Craiova, Romania.
Department of Obstetrics and Gynecology, "Filantropia" Hospital from Craiova.
Curr Health Sci J. 2022 Apr-Jun;48(2):162-168. doi: 10.12865/CHSJ.48.02.04. Epub 2022 Jun 30.
To compare the ability of cervical length (CL), anterior cervical angle (ACA), and cervical consistency index (CCI) to predict premature birth.
This prospective study involved 85 pregnant women who gave birth prematurely and a control group of 31 pregnant women who gave birth at term. The study was performed in the Obstetrics and Gynecology Clinic of the Municipal Clinical Hospital Filanthropia Craiova between January 1, 2019, and January 1, 2022. Cases were examined using transvaginal ultrasonography (TVU) in the second and third trimesters of pregnancy, and cervical length (CL), Anterior Cervical Angle (ACA), and Cervical Consistency Index (CCI) were measured.
The mean value from the three measurements at all three parameters was statistically significant with preterm birth (p<0.05). Cervical length <25mm, was highly significant in the prediction of preterm labor with a sensitivity of 99%, specificity of 61%, positive predictive value (PPV) of 78%, negative predictive value (NPV) of 97 %, and a positive likelihood ratio (LR+) of 2.54 and negative likelihood ratio (LR-) of 0.02. CCI also remains, despite low specificity and PPV values, a potential predictive parameter in the prediction of preterm birth, with a sensitivity of 73%, NPV of 92% and a LR+of 1.32 and LR- of 0.6 also correlated with CL, CCI being more difficult to interpret as an independent predictive parameter.
CL remains the standard parameter for predicting the preterm birth, but in combination with other parameters, the prediction rate can increase significantly.
比较宫颈长度（CL）、宫颈前角（ACA）和宫颈硬度指数（CCI）预测早产的能力。
这项前瞻性研究纳入了85例早产孕妇和31例足月产孕妇作为对照组。该研究于2019年1月1日至2022年1月1日在克拉约瓦市慈善市立医院妇产科诊所进行。在妊娠中期和晚期使用经阴道超声检查（TVU）对病例进行检查，并测量宫颈长度（CL）、宫颈前角（ACA）和宫颈硬度指数（CCI）。
所有三个参数的三次测量平均值与早产有统计学意义（p<0.05）。宫颈长度<25mm对早产的预测具有高度显著性，敏感性为99%，特异性为61%，阳性预测值（PPV）为78%，阴性预测值（NPV）为97%，阳性似然比（LR+）为2.54且阴性似然比（LR-）为0.02。尽管特异性和PPV值较低，但CCI仍是预测早产的一个潜在预测参数，敏感性为73%，NPV为92%，LR+为1.32且LR-为0.6，也与CL相关，CCI作为一个独立的预测参数更难解释。
CL仍然是预测早产的标准参数，但与其他参数结合使用时，预测率可显著提高。
