SDM Craniofacial surgery and research centre, SDM College of dental sciences and hospital, Shri Dharmasthala Manjunatheswara University, Sattur, Dharwad - 580009, Karnataka, India.
Stomatologija. 2022;24(1):26-32.
Acantholytic Squamous Cell Carcinoma (ASCC) is an uncommon histopathologic variant of Squamous Cell Carcinoma which occurs in the sun-exposed skin and rarely in the oral cavity. Although the World Health Organization (WHO) has defined ASCC as a unique entity, its occurrence in the oral cavity has been just about 60 cases in the literature. There have been cases reported in the lips, tongue, gingiva and maxillary alveolus but rarely in the mandible. Definitive diagnosis and treatment of such a rare condition is challenging as there are not much available data in the literature. We report a rare case of Acantholytic Squamous cell carcinoma with pathologic fracture of the mandible which was managed aptly considering its hostile clinical, radiological and histological presentation. The reconstruction was done using a vascularised free fibula graft which helped in achieving a functional and aesthetic rehabilitation for the patient thereby improving his quality of life.
棘层松解性鳞状细胞癌（ASCC）是一种罕见的鳞状细胞癌组织病理学变异型，发生在暴露于阳光的皮肤，很少发生在口腔。尽管世界卫生组织（WHO）将 ASCC 定义为一种独特的实体，但在文献中仅报道了约 60 例口腔发生的病例。在唇部、舌部、牙龈和上颌牙槽骨中已有报道，但在下颌骨中很少见。由于文献中没有太多可用的数据，因此对这种罕见疾病的明确诊断和治疗具有挑战性。我们报告了一例罕见的伴有下颌骨病理性骨折的棘层松解性鳞状细胞癌病例，根据其具有侵袭性的临床、影像学和组织学表现，对其进行了适当的治疗。使用带血管游离腓骨移植进行了重建，这有助于为患者实现功能和美学康复，从而提高了他的生活质量。
