Zheng Bin, Liu Zhenghong, Wang Heng, Wang Jinxue, Zhang Pu, Zhang Dahong
Urology and Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Front Oncol. 2022 Oct 17;12:972676. doi: 10.3389/fonc.2022.972676. eCollection 2022.
To investigate the relationship between orthotopic U-shaped ileal neobladder volume and bladder function. To investigate the correlation between the volume of the radical cystectomy and the U-shaped ileal neobladder and the function of the bladder.
The clinical data of patients undergoing in orthotopic U-shaped neobladder in our hospital were retrospectively analyzed. They were divided into two groups according to the length of the retained ileum. Group 1: The length of the ileum was 25-35cm (including 35cm), and the second group: the length of the ileum was 35-45cm. The basic information, cushion usage, urodynamic examination and complications of the two groups were obtained.
A total of 88 patients were included in the study, including 33 in the first group and 55 in the second group. There was no statistical difference in general data, lymph node collection, lymph node positive rate, positive margin rate, postoperative pathological stage, pathological grade, pathological type, intraoperative blood loss, blood transfusion, postoperative hospital stay, and complications between the two groups of patients. significance. Although the usage of urine pads in group 1 was more than that in group 2 in the short term after operation (P<0.05), it started from the third year after operation. Patients in group 1 used less cushion than group 2 (P<0.05). Urodynamic examination was performed on the patients, and the bladder function of group 1 maintained satisfactory time longer than that of group 2. The total number of deaths in the two groups was 12 and 23, respectively. The 5-year overall survival (OS) rate of group 1 was 53.60%, and the 5-year overall survival rate of group 2 was 52.9%.
A new bladder formed by cutting the ileum with a length of 25-35 cm (including 35cm) has a longer time to maintain good bladder function than cutting the ileum with a length of 35-45 cm to produce a new bladder.
探讨原位U形回肠新膀胱容量与膀胱功能之间的关系。探讨根治性膀胱切除术及U形回肠新膀胱的容量与膀胱功能之间的相关性。
回顾性分析我院行原位U形新膀胱术患者的临床资料。根据保留回肠的长度将其分为两组。第一组：回肠长度为25 - 35cm（含35cm），第二组：回肠长度为35 - 45cm。获取两组患者的基本信息、尿垫使用情况、尿动力学检查及并发症情况。
本研究共纳入88例患者，其中第一组33例，第二组55例。两组患者的一般资料、淋巴结清扫情况、淋巴结阳性率、切缘阳性率、术后病理分期、病理分级、病理类型、术中出血量、输血情况、术后住院时间及并发症等方面比较，差异均无统计学意义。虽然术后短期内第一组尿垫使用量多于第二组（P<0.05），但从术后第三年开始，第一组患者尿垫使用量少于第二组（P<0.05）。对患者进行尿动力学检查，第一组膀胱功能维持满意时间长于第二组。两组死亡总数分别为12例和23例。第一组5年总生存率为53.60%，第二组5年总生存率为52.9%。
截取长度为25 - 35cm（含35cm）的回肠形成的新膀胱，其维持良好膀胱功能的时间比截取长度为35 - 45cm的回肠形成新膀胱的时间长。
