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192711 名体重过轻和正常体重工人的心血管风险测定。

Determination of cardiovascular risk in 192,711 underweight and normal weight workers.

机构信息

Balearic Islands Health Service, Balearic Islands, Spain.

University School ADEMA Palma, Balearic Islands, Spain.

出版信息

Turk J Med Sci. 2022 Aug;52(4):926-933. doi: 10.55730/1300-0144.5392. Epub 2022 Aug 10.

DOI:10.55730/1300-0144.5392
PMID:36326367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10387884/
Abstract

BACKGROUND

The aim of this study was to determine the prevalence of cardiovascular risk factors (CVRF) and the level of cardiovascular risk (CVR), determined with different scales (REGICOR, SCORE, ERICE, vascular age...) in people with low and normal weight.

METHODS

A total of 192,711 underweight and normal weight Spanish workers participated. CVR parameters included were weight, abdominal circumference, blood pressure, glycemia (high >125 mg/dL or under hypoglycemic treatment) and lipids (cutoff points: total cholesterol 200 mg/dL, LDL 130 mg/dL, triglycerides 150 mg/dL) were obtained by automated enzymatic methods. Body mass index (BMI) was calculated, considering underweight 18.5 and normal weight 18.5-24.9. A descriptive analysis of the categorical variables was carried out.

RESULTS

The values of analytical, anthropometric and clinical parameters were more unfavorable in the normal weight group. Also, the prevalence of alterated values of CVR seen with different scales show higher risk in this group and in all cases the values in men are worse. It was seen that the variable with the greatest influence on the appearance of altered values of the cardiovascular risk scales (CVRS), influencing all of them was the age.

DISCUSSION

All the CVRS analyzed showed higher values in the group of people with normal weight compared to those with underweight. Age, followed by sex, were the variables that most influence the appearance of high CVR values.

摘要

背景

本研究旨在确定低体重和正常体重人群中心血管危险因素(CVRF)的患病率和心血管风险(CVR)水平,这些风险是通过不同的量表(REGICOR、SCORE、ERICE、血管年龄等)确定的。

方法

共有 192711 名体重过轻和正常的西班牙工人参与了这项研究。通过自动酶学法获得了 CVR 参数,包括体重、腰围、血压、血糖(高>125mg/dL 或正在接受低血糖治疗)和血脂(切点:总胆固醇 200mg/dL、LDL 130mg/dL、甘油三酯 150mg/dL)。通过计算身体质量指数(BMI),将体重过轻定义为 18.5,正常体重定义为 18.5-24.9。对分类变量进行了描述性分析。

结果

在正常体重组中,分析、人体测量和临床参数的值更不利。此外,不同量表所见的 CVR 改变值的患病率显示出该组更高的风险,而且在所有情况下,男性的值更差。结果发现,对心血管风险量表(CVRS)改变值出现的影响最大的变量是年龄,所有这些变量都受到年龄的影响。

讨论

所有分析的 CVRS 在正常体重组中显示出比体重过轻组更高的值。年龄,其次是性别,是影响高 CVR 值出现的最重要变量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ac/10387884/c89a1f9d008f/turkjmedsci-52-4-926f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ac/10387884/c89a1f9d008f/turkjmedsci-52-4-926f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ac/10387884/c89a1f9d008f/turkjmedsci-52-4-926f1.jpg

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