Faundes A, Sivin I, Stern J
Contraception. 1978 Oct;18(4):355-65. doi: 10.1016/0010-7824(78)90023-9.
The menstrual patterns of women using subdermal implants of levonorgestrel and norgestrienone included in a double-blind clinical trial was evaluated by the method developed by the International Committee on Contraception Research. Women using Copper T200 randomly selected in the same clinics were used as controls. Both implant regimens were associated with a high frequency of reduced bleeding and norgestrel patients had also a high proportion of increased and irregular bleeding. Termination of use was associated to increased bleeding but not so much to reduced bleeding.
采用国际避孕研究委员会开发的方法,对一项双盲临床试验中使用左炔诺孕酮和炔诺孕烯酮皮下植入剂的女性月经模式进行了评估。在相同诊所中随机选取使用铜T200的女性作为对照。两种植入方案都与出血减少的高频率相关,且使用左炔诺孕酮的患者出现出血增多和不规则出血的比例也很高。终止使用与出血增加有关,但与出血减少关系不大。