Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, University of Lleida, Lleida, Spain.
Meta-Analysis Unit, Department of Basic Psychology and Methodology, University of Murcia, Murcia, Spain.
Nurs Open. 2023 Mar;10(3):1270-1280. doi: 10.1002/nop2.1449. Epub 2022 Nov 6.
To systematically evaluate the efficacy of different topical treatments for PVC-related phlebitis in hospital in-patients.
A systematic review and meta-analysis.
A selection was made of experimental and quasi-experimental studies published in English or Spanish. These should provide data on the degree of phlebitis, pain and infiltration (means and standard deviations, mainly) of hospitalized patients with phlebitis secondary to peripheral venous catheter. All those studies that reflected systemic or exclusive prevention treatments were excluded. Searches were from inception to April 2020. The date of data collection was from December 2020 to May 2021. The selection criteria were based on the PICOS model. Risk of bias was assessed using the Cochrane Collaboration tool.
Twelve studies (726 patients) met the inclusion criteria. With respect to the decrease in the degree of phlebitis, was found ichthammol glycerine, followed by heparinoids. As for degree of pain, sesame oil obtained the most marked reduction. In terms of degree of infiltration, heparinoids and ichthammol glycerine were the only products to achieve a statistically significant reduction. The most important limitations are the low quantity and quality of the trials included. Insufficient data are available to draw valid conclusions about the efficacy of any treatment.
系统评估不同局部治疗方案对医院住院患者 PVC 相关静脉炎的疗效。
系统评价和荟萃分析。
选择发表于英文或西文的实验性和准实验性研究。这些研究应提供与外周静脉导管相关静脉炎住院患者的静脉炎、疼痛和浸润程度（主要为均值和标准差）相关的数据。所有反映全身或专门预防治疗的研究均被排除。检索时间为从建库至 2020 年 4 月。数据收集日期为 2020 年 12 月至 2021 年 5 月。选择标准基于 PICOS 模型。使用 Cochrane 协作工具评估偏倚风险。
符合纳入标准的有 12 项研究（726 例患者）。在静脉炎程度的降低方面，发现甘汞甘油和肝素类效果最好。在疼痛程度方面，芝麻油的缓解效果最明显。在浸润程度方面，只有肝素类和甘汞甘油能够显著降低浸润程度。最重要的局限性是纳入的试验数量和质量较低。目前尚无足够数据可以对任何治疗方案的疗效得出有效结论。
