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术语更新:最佳呼气末正压

Terminology update: optimal PEEP.

作者信息

Gallagher T J, Civetta J M, Kirby R R

出版信息

Crit Care Med. 1978 Sep-Oct;6(5):323-6. doi: 10.1097/00003246-197809000-00005.

Abstract

The term, optimal PEEP, requires redefinition in the light of new clinical data. With the onset of acute respiratory failure heralded by blood gas evidence of decreased oxygenation, PEEP is supplied in quantities sufficient to restore intrapulmonary shunt (Qsp/Qt) to a preselected goal of 15%. This is compatible with published criteria defining adequate blood gas exchange. Now rather than permitting reduction of cardiac output to be the end point of PEEP application, selective cardiovascular interventions to support preload, contractility, or afterload are made as appropriate so that cardiac function may be maintained until the preselected endpoint of shunt reduction of 15% can be made.

摘要

鉴于新的临床数据,“最佳呼气末正压(optimal PEEP)”这一术语需要重新定义。随着急性呼吸衰竭的发生,血气显示氧合降低,给予足够量的呼气末正压以使肺内分流(Qsp/Qt)恢复到预先设定的15%的目标值。这与已发表的定义充分血气交换的标准相符。现在,不是将心输出量降低作为应用呼气末正压的终点,而是根据需要进行选择性心血管干预以支持前负荷、收缩力或后负荷,从而维持心脏功能,直到可以实现预先设定的将分流降低15%的终点。

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