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[酵母缬氨酸tRNA1 D臂片段及其类似物的合成]

[Synthesis of fragments of the D-branch of yeast valine tRNA1 and their analogs].

作者信息

Zhenodarova S M, Kliagina V P, Sedel'nikova E A, Smol'ianinova O A

出版信息

Bioorg Khim. 1986 Feb;12(2):220-9.

PMID:3633726
Abstract

Nonanucleotide GpUpCpUpApGpDpCpGp corresponding to the fragment 10-18 of the yeast tRNA1Val with pseudouridine-13 replaced by uridine has been synthesized. Dihydrouridine derivatives were studied as substrated of ribonucleases with various specificity and of RNA ligase.

摘要

已合成了与酵母tRNA1Val的第10 - 18片段相对应的九核苷酸GpUpCpUpApGpDpCpGp,其中假尿苷-13被尿苷取代。对二氢尿苷衍生物作为具有不同特异性的核糖核酸酶和RNA连接酶的底物进行了研究。

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