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局部麻醉药持续伤口灌注:对接受择期乳房切除术患者疼痛评分和阿片类药物使用的影响。

Continuous local anesthetic wound infusion: Impact on pain score and opioid use in patients undergoing elective mastectomy.

作者信息

AlFaraj Ahmed, AlFaraidy Mona, AlZaher Zaki, Al Wosaibai Adnan, AlShabeb Abduladem K, AlHashim Hussain, AlKhulaif Zainab

机构信息

King Fahad Specialist Hospital, Dammam, Saudi Arabia.

Dammam Medical Complex, Dammam, Saudi Arabia.

出版信息

Saudi J Anaesth. 2022 Oct-Dec;16(4):374-378. doi: 10.4103/sja.sja_874_21. Epub 2022 Sep 3.

Abstract

INTRODUCTION

Opioids are commonly used to control acute postoperative pain but their usage is associated with significant complications and the potential of addiction. This study was designed to assess the effect of a Continuous Local Anesthetic Wound Infusion Catheter (CLAWIC) on pain score and as an opioid-sparing agent in patients undergoing elective mastectomy.

METHOD

The search was done using all patients' record from February 2013 to February 2018. The data were collected through the acute pain service database, operation room lists, surgical site infection database, acute pain service sheet, and anesthesia sheet. The patients inclusion criteria were adults who underwent elective mastectomy surgery at King Fahad Specialist Hospital. Patient age, sex, weight, and height were also recorded.

RESULT

The opioid use intraoperatively and postoperatively was significantly lower in the CLAWIC than in the control group. Also, accumulative opioid use was significantly lower in the CLAWIC group. From transfer to the PACU until 48 hours postoperatively, the percentage of patients requiring opioids was significantly lower in the CLAWIC group. After 48 hours, there was no difference in opioid use between the two groups. Visual Analog Scale (VAS) pain scores were significantly lower in the CLAWIC than in the control group.

CONCLUSION

CLWIC showed opioid-sparing effects following mastectomy, as shown by a significantly lower mean opioid dose and a lower percentage of subjects needing opioid analgesia. The procedure is easy to perform and relatively safe. CLWIC could reduce opioid consumption while maintaining good postoperative pain control.

摘要

引言

阿片类药物常用于控制术后急性疼痛,但其使用会引发严重并发症及成瘾风险。本研究旨在评估连续局部麻醉伤口输注导管(CLAWIC)对择期乳房切除术患者疼痛评分的影响,并作为一种阿片类药物节省剂。

方法

检索了2013年2月至2018年2月期间所有患者的记录。数据通过急性疼痛服务数据库、手术室清单、手术部位感染数据库、急性疼痛服务表和麻醉表收集。纳入标准为在法赫德国王专科医院接受择期乳房切除术的成年人。还记录了患者的年龄、性别、体重和身高。

结果

CLAWIC组术中及术后的阿片类药物使用量显著低于对照组。此外,CLAWIC组的累积阿片类药物使用量也显著较低。从转运至PACU直至术后48小时,CLAWIC组中需要阿片类药物的患者百分比显著较低。48小时后,两组之间的阿片类药物使用量无差异。CLAWIC组的视觉模拟量表(VAS)疼痛评分显著低于对照组。

结论

乳房切除术后,CLWIC显示出阿片类药物节省效果,表现为平均阿片类药物剂量显著降低,且需要阿片类镇痛的受试者百分比更低。该操作易于实施且相对安全。CLWIC可减少阿片类药物的消耗,同时保持良好的术后疼痛控制。

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