Montagne William, Wang Robert C
Otolaryngology - Head and Neck Surgery, University of Nevada Las Vegas School of Medicine, Las Vegas, USA.
Cureus. 2022 Oct 2;14(10):e29839. doi: 10.7759/cureus.29839. eCollection 2022 Oct.
Cowden syndrome (CS) is an autosomal dominant condition that is relatively rare. CS patients can have tumors derived from all three germlines. They can present with mucocutaneous hamartomas or other benign tumors, and have an increased risk of malignancies of the thyroid, breast, kidney, GI tract, and skin. In our clinic, a 40-year-old CS patient presented for thyroidectomy after fine needle aspiration was suspicious for papillary thyroid carcinoma (PTC). Another major concern was the cosmetic appearance of her lips, which were diffusely covered with small hamartomas. We were able to remove these in a novel manner using a cavitron ultrasonic surgical aspirator (CUSA; Integra Lifesciences, Princeton, NJ, USA). Using the CUSA tangential to the lip surface allowed for removal of the hamartomas in a way that created a smooth and cosmetically appealing outcome for the patient. The use of an ultrasonic surgical aspirator is a novel way to cosmetically treat hamartomas of the lip for CS patients.
考登综合征（CS）是一种相对罕见的常染色体显性遗传病。CS患者可能会出现源自所有三个胚层的肿瘤。他们可能表现为皮肤黏膜错构瘤或其他良性肿瘤，并且患甲状腺、乳腺、肾脏、胃肠道和皮肤恶性肿瘤的风险增加。在我们的诊所，一名40岁的CS患者在细针穿刺怀疑为甲状腺乳头状癌（PTC）后前来接受甲状腺切除术。另一个主要问题是她的嘴唇外观，上面布满了小错构瘤。我们能够使用超声外科吸引器（CUSA；Integra Lifesciences，美国新泽西州普林斯顿）以一种新颖的方式将这些错构瘤切除。将CUSA与嘴唇表面相切使用，可以以一种为患者创造出平滑且美观效果的方式切除错构瘤。使用超声外科吸引器是一种为CS患者进行嘴唇错构瘤美容治疗的新颖方法。
