Field Epidemiology Training Program, Freetown, Sierra Leone.
Centers for Disease Control and Prevention (CDC), Georgia, United States.
Pan Afr Med J. 2022 Aug 8;42:256. doi: 10.11604/pamj.2022.42.256.35838. eCollection 2022.
the Kenema District Surveillance team in Sierra Leone received notifications of patients with suspected Lassa fever on February 20 and March 2, 2019. On that day, an investigation started to confirm the diagnosis and search for additional cases.
we used the Lassa fever surveillance case definition and collected demographic and exposure information from suspected cases through interviews and clinical records. Blood samples were collected from the cases to confirm the diagnosis. Active case finding was conducted in the community and health facility.
on February 10, 2019, an eight-year-old male developed a fever (>39.5°C) and a sore throat. On February 18, 2019, he was admitted to a hospital and treated for malaria and pneumonia. On February 20, 2019, Lassa fever was suspected because the patient was bleeding from orifices and testing. On February 15, a 5-year-old female developed fever and headache and was treated with anti-malarial drugs. On February 26 the high fever re-emerged with severe bleeding from the orifices. She was admitted and treated with antibiotics, confirmed for Lassa fever, and died on March 2, 2019.
the two children had Lassa fever, and no additional cases were identified. We sensitized clinicians on suspicion of Lassa fever to improve early detection and treatment.
塞拉利昂凯内马地区监测小组于 2019 年 2 月 20 日和 3 月 2 日收到疑似拉沙热患者的通知。当天，开始进行调查以确认诊断并寻找其他病例。
我们使用拉沙热监测病例定义，通过访谈和临床记录从疑似病例中收集人口统计学和暴露信息。采集血样以确认诊断。在社区和卫生机构中开展主动病例搜索。
2019 年 2 月 10 日，一名 8 岁男童出现发热（>39.5°C）和咽痛。2 月 18 日，他因疟疾和肺炎住院治疗。2019 年 2 月 20 日，由于患者出现出血和检测结果，怀疑患有拉沙热。2 月 15 日，一名 5 岁女童出现发热和头痛，并用抗疟药物治疗。2 月 26 日，高热再次出现，伴有严重的口鼻出血。她入院后接受抗生素治疗，确诊为拉沙热，并于 2019 年 3 月 2 日死亡。
这两名儿童患有拉沙热，未发现其他病例。我们提高了临床医生对拉沙热疑似病例的敏感性，以改善早期发现和治疗。
