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冲突后塞拉利昂拉沙热数据集。

Data set on Lassa fever in post-conflict Sierra Leone.

作者信息

Shaffer Jeffrey G, Schieffelin John S, Grant Donald S, Goba Augustine, Momoh Mambu, Kanneh Lansana, Levy Danielle C, Hartnett Jessica N, Boisen Matt L, Branco Luis M, Garry Robert F

机构信息

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Departments of Pediatrics and Internal Medicine, Sections of Pediatric and Adult Infectious Diseases, Tulane University School of Medicine, New Orleans, LA, United States.

出版信息

Data Brief. 2019 Jan 16;23:103673. doi: 10.1016/j.dib.2019.01.021. eCollection 2019 Apr.

DOI:10.1016/j.dib.2019.01.021
PMID:30788396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6369334/
Abstract

Lassa fever is a rodent-borne illness that is endemic to parts of sub-Saharan Africa, including Sierra Leone, Nigeria, and Guinea. The disease is named after the town of Lassa, Nigeria where it was discovered in 1969. This data article focuses on the epidemiology of Lassa fever in Sierra Leone following a decade-long civil war that ended in 2002. The data were collected at Kenema Government Hospital (KGH) in Kenema, Sierra Leone, which maintains the country׳s only Lassa fever treatment facility and a biosafety level 3 (BSL-3) laboratory. The key data set variables include Lassa fever serostatus determined using antigen (Ag), immunoglobulin M (IgM), and immunoglobulin G (IgG) ELISA diagnostic techniques; and patient demographics, survival outcome, and treatment (ribavirin) status. The individual data used to generate the graphs and tables in the corresponding research manuscript published in in 2014 and its coding guide are provided as Supplementary material (Shaffer et al., 2014) [1].

摘要

拉沙热是一种由啮齿动物传播的疾病,在撒哈拉以南非洲的部分地区流行,包括塞拉利昂、尼日利亚和几内亚。该疾病以尼日利亚的拉沙镇命名,1969年在那里被发现。这篇数据文章聚焦于2002年结束的长达十年的内战之后塞拉利昂的拉沙热流行病学情况。数据是在塞拉利昂凯内马的凯内马政府医院(KGH)收集的,该医院设有该国唯一的拉沙热治疗设施和一个生物安全三级(BSL-3)实验室。关键数据集变量包括使用抗原(Ag)、免疫球蛋白M(IgM)和免疫球蛋白G(IgG)酶联免疫吸附测定诊断技术确定的拉沙热血清状态;以及患者人口统计学信息、生存结果和治疗(利巴韦林)状态。用于生成2014年发表的相应研究手稿中的图表的个体数据及其编码指南作为补充材料提供(Shaffer等人,2014年)[1]。

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本文引用的文献

1
Lassa fever in post-conflict sierra leone.塞拉利昂冲突后地区的拉萨热疫情。
PLoS Negl Trop Dis. 2014 Mar 20;8(3):e2748. doi: 10.1371/journal.pntd.0002748. eCollection 2014 Mar.
2
Emerging trends in Lassa fever: redefining the role of immunoglobulin M and inflammation in diagnosing acute infection.拉沙热的新趋势:重新定义免疫球蛋白 M 和炎症在诊断急性感染中的作用。
Virol J. 2011 Oct 24;8:478. doi: 10.1186/1743-422X-8-478.
3
New opportunities for field research on the pathogenesis and treatment of Lassa fever.拉沙热发病机制与治疗的现场研究新机遇。
Antiviral Res. 2008 Apr;78(1):103-15. doi: 10.1016/j.antiviral.2007.11.003. Epub 2007 Dec 17.
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Technical efficiency of peripheral health units in Pujehun district of Sierra Leone: a DEA application.塞拉利昂普杰洪区基层医疗卫生单位的技术效率:数据包络分析应用
BMC Health Serv Res. 2005 Dec 14;5:77. doi: 10.1186/1472-6963-5-77.
5
Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses.拉沙病毒(约西亚株)S基因组RNA的核苷酸序列以及N和GPC蛋白与其他沙粒病毒的氨基酸序列比较。
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