Gossili Farid, Carlé Allan, Andersen Trine B, Zacho Helle D
Department of Nuclear Medicine, Aalborg University Hospital, Aalborg, Denmark.
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark.
Case Rep Endocrinol. 2022 Oct 26;2022:7712097. doi: 10.1155/2022/7712097. eCollection 2022.
Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (Tc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosphatemia, and vitamin D insufficiency. The patient complained of cerebral symptoms and intermittent abdominal discomfort without constipation. After surgical removal of the hyperactive parathyroid gland and D vitamin supplementation, all blood tests were normalized. The clinical and paraclinical characteristics of GPA may raise the suspicion of parathyroid carcinoma, but not absolutely in this case.
甲状旁腺腺瘤是原发性甲状旁腺功能亢进症（PHPT）最常见的病因。我们报告了1例甲状旁腺激素严重升高、高钙血症、低磷血症和维生素D缺乏的患者，术前通过（Tc）-甲氧基异丁基异腈甲状旁腺闪烁扫描术检测出巨大甲状旁腺腺瘤（GPA）。患者主诉有脑部症状和间歇性腹部不适，但无便秘。手术切除功能亢进的甲状旁腺并补充维生素D后，所有血液检查结果均恢复正常。GPA的临床和辅助检查特征可能会让人怀疑甲状旁腺癌，但本病例并非绝对如此。
