From the Departments of Nuclear Medicine and Molecular Imaging.
Hemato-Oncology, Sanjeevani CBCC USA Cancer Hospital, Raipur, Chhattisgarh, India.
Clin Nucl Med. 2022 Dec 1;47(12):e746-e748. doi: 10.1097/RLU.0000000000004415. Epub 2022 Sep 30.
Early T-cell precursor ALL (acute lymphoblastic leukemia) is a rare type of childhood and adult T-cell ALL. Disease recurrence is common within 2 years from the time of initial diagnosis. Outcomes of relapse have been characterized through risk stratification schemes, and one of the major determinants of overall survival is the overall tumor burden and sites of relapse. Although testicular recurrence is common; Peripheral nerve as a site of recurrence is relatively rare. We present a case of early T-cell ALL on maintenance therapy with multifocal relapse on FDG PET/CT in the cervical lymph nodes, the testis, and the left sciatic nerve. Bone marrow and flow cytometry confirmed the relapse.
早期 T 细胞前体急性淋巴细胞白血病（T-cell precursor ALL）是一种罕见的儿童和成人 T 细胞 ALL 类型。疾病复发在初始诊断后 2 年内很常见。通过风险分层方案对复发的结果进行了描述，并且总体生存的主要决定因素之一是总体肿瘤负担和复发部位。尽管睾丸复发很常见，但作为复发部位的周围神经相对罕见。我们报告了一例维持治疗期间的早期 T 细胞 ALL 病例，在氟脱氧葡萄糖 PET/CT 上显示在颈部淋巴结、睾丸和左坐骨神经上出现多灶性复发。骨髓和流式细胞术证实了复发。
