68Ga-FAPI-04在鉴别嫌色性肾细胞癌软组织和肝转移灶用于再分期中的优势

Superiority of 68Ga-FAPI-04 in Delineation of Soft Tissue and Liver Metastases in Chromophobe Renal Cell Carcinoma for Restaging.

作者信息

Xie Fei, Fu Lilan, Zhou Wenlan

机构信息

From the Department of NanFang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China.

出版信息

Clin Nucl Med. 2022 Dec 1;47(12):e758-e759. doi: 10.1097/RLU.0000000000004374. Epub 2022 Aug 12.

DOI:10.1097/RLU.0000000000004374

PMID:36342807

Abstract

Chromophobe renal cell carcinoma (RCC) is a rare tumor. We described findings of 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT of metastatic chromophobe RCC in a 56-year-old woman. 68Ga-FAPI-04 PET/CT demonstrated that the metastatic lesions in the liver, left posterior abdominal wall, and the left waist had intense uptake of 68Ga-FAPI-04, which was higher than that of 18F-FDG on 18F-FDG PET/CT. 68Ga-FAPI-04 PET/CT also delineated the metastatic lesions more clearly than 18F-FDG PET/CT. This case highlights 68Ga-FAPI-04 PET/CT may be promising in restaging of chromophobe RCC.

摘要

嫌色性肾细胞癌（RCC）是一种罕见肿瘤。我们描述了一名56岁女性转移性嫌色性RCC的18F-FDG PET/CT和68Ga-FAPI-04 PET/CT检查结果。68Ga-FAPI-04 PET/CT显示肝脏、左后腹壁和左腰部的转移病灶对68Ga-FAPI-04摄取强烈，高于18F-FDG PET/CT上18F-FDG的摄取。68Ga-FAPI-04 PET/CT也比18F-FDG PET/CT更清晰地勾勒出转移病灶。该病例表明68Ga-FAPI-04 PET/CT在嫌色性RCC再分期方面可能很有前景。