一名严重免疫抑制的HIV感染患者发生无脑膜受累的慢性播散性隐球菌病，用氟康唑成功治疗。
Chronic disseminated cryptococcosis without meningeal involvement in a severely immunosuppressed HIV-infected patient successfully treated with fluconazole.
作者信息
Yonekura Tatiane da Silveira, Macedo Soraya Devi, Moya Fernanda Gonçalves, Vidal José Ernesto
机构信息
Instituto de Infectologia Emilio Ribas, Av. Dr. Arnaldo 165, São Paulo, 01246-900, Brazil.
Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Av. Doutor Enéas Carvalho Aguiar 255, 05403-000, São Paulo, Brazil.
出版信息
Med Mycol Case Rep. 2022 Oct 28;38:30-32. doi: 10.1016/j.mmcr.2022.10.001. eCollection 2022 Dec.
A 43-year-old female with advanced HIV infection presented with two chronic skin lesions. Cutaneous cryptococcosis was confirmed and pulmonary cryptococcosis was suspected. The patient was neurologically asymptomatic and the cerebrospinal fluid cryptococcal antigen lateral flow assay was negative. She received oral fluconazole and had resolution of the skin lesions and significant improvement of the lung lesions. We report a person with AIDS with chronic disseminated cryptococcosis without meningeal involvement successfully treated with oral fluconazole.
一名43岁晚期HIV感染女性出现两处慢性皮肤病变。皮肤隐球菌病得到确诊，肺部隐球菌病疑似存在。该患者无神经系统症状，脑脊液隐球菌抗原侧向流动分析呈阴性。她接受了口服氟康唑治疗，皮肤病变消退，肺部病变显著改善。我们报告了一例艾滋病患者，患有慢性播散性隐球菌病且无脑膜受累，经口服氟康唑成功治愈。
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