Hong Bennett Y, Fortune Brad, Kinast Robert M, Burgoyne Claude F, Rees Jack P, Mansberger Steven L
Legacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USA.
Am J Ophthalmol Case Rep. 2022 Oct 20;28:101733. doi: 10.1016/j.ajoc.2022.101733. eCollection 2022 Dec.
Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT).
OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours.
AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function.
青光眼与视神经乳头的结构变化相关，如变形、筛板缺损、板层前劈裂和视乳头周围视网膜劈裂。我们描述了通过常规光谱域光学相干断层扫描（OCT）检测到的视神经空洞。
OCT成像显示，4例初诊为青光眼或青光眼可疑患者的5只眼中存在空洞。这些空洞表现为与周围组织界限清晰的低反射区。它们位于鼻下，筛板前方，至少部分位于布鲁赫膜开口（BMO）内。它们从3点延伸到6点。
我们描述了在诊断为青光眼和青光眼可疑患者中的一项新的OCT发现。虽然之前的报告描述了病理性近视患者脉络膜中的空洞，但我们的患者屈光不正极小，且空洞位于视神经内。我们将长期观察这些患者，以确定这一发现对结构和功能纵向变化的影响。
