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病理性近视眼中的乳头和视盘周围区域的结构异常及其对应的视野缺损。

Structural Abnormalities in the Papillary and Peripapillary Areas and Corresponding Visual Field Defects in Eyes With Pathologic Myopia.

机构信息

Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):13. doi: 10.1167/iovs.63.4.13.

DOI:10.1167/iovs.63.4.13
PMID:35446343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9034715/
Abstract

PURPOSE

To identify structural abnormalities in the papillary and peripapillary area in eyes with pathologic myopia (PM) and normal IOP and to determine their relationship to visual field (VF) defects.

METHODS

One hundred eight eyes of 70 patients with PM were retrospectively studied. The disc-centered swept source optical coherence tomographic images and the Goldmann VF recorded within 1 year of the optical coherence tomographic examination were analyzed. Four structural abnormalities were identified: lamina cribrosa (LC) defects, ridge protrusions, intrachoroidal cavitations (ICC), and prelaminar schisis. The correspondence of the VF defects with the structural abnormalities was assessed.

RESULTS

The mean age, axial length, and optic disc area of the 108 eyes were 58.7 ± 10.0 years, 31.1 ± 2.4 mm, and 4.7 ± 2.2 mm2, respectively. Eighty-five of the 108 eyes (78.7%) had at least one abnormality and 49.4% (42/85) had two or more abnormalities. LC defects, ridge protrusions, ICC, and prelaminar schisis were detected in 47.2%, 33.3%, 21.3%, and 30.6% of the eyes, respectively. VF defects at the corresponding areas of these structural abnormalities were seen in 63% of the eyes with LC defects, 39% of the eyes with ridge protrusions, and 21% of the eyes with ICC.

CONCLUSIONS

Four kinds of structural abnormalities with corresponding VF defects are commonly observed in the papillary and peripapillary region of eyes with PM. The presence of these abnormalities suggests a possibility of functional damage.

摘要

目的

在眼压正常的病理性近视（PM）眼的乳头和视盘周围区域识别结构异常，并确定其与视野（VF）缺损的关系。

方法

回顾性研究了 70 例 PM 患者的 108 只眼。对以视盘为中心的扫频源光学相干断层扫描图像和光学相干断层扫描检查后 1 年内记录的 Goldmann VF 进行了分析。共发现 4 种结构异常：筛板缺陷、脊突、脉络膜内陷和视盘前裂。评估了 VF 缺损与结构异常的对应关系。

结果

108 只眼中的平均年龄、眼轴长度和视盘面积分别为 58.7±10.0 岁、31.1±2.4mm 和 4.7±2.2mm²。108 只眼中 85 只（78.7%）至少存在 1 种异常，49.4%（42/85）存在 2 种或更多异常。47.2%、33.3%、21.3%和 30.6%的眼中分别发现了筛板缺陷、脊突、脉络膜内陷和视盘前裂。在 63%的存在筛板缺陷的眼中、39%的存在脊突的眼中和 21%的存在脉络膜内陷的眼中，相应区域可见 VF 缺损。

结论

在 PM 眼的乳头和视盘周围区域，常见到 4 种伴有相应 VF 缺损的结构异常。这些异常的存在提示存在功能损伤的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/02b836f1cc04/iovs-63-4-13-f008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/ff4589b29c8a/iovs-63-4-13-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/9b360566f05f/iovs-63-4-13-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/dbf8bc833776/iovs-63-4-13-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/dc9474221e33/iovs-63-4-13-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/23b3cdb48e28/iovs-63-4-13-f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/ded1c32fe604/iovs-63-4-13-f006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/9e5a6b36c919/iovs-63-4-13-f007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/02b836f1cc04/iovs-63-4-13-f008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/ff4589b29c8a/iovs-63-4-13-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/9b360566f05f/iovs-63-4-13-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/dbf8bc833776/iovs-63-4-13-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/dc9474221e33/iovs-63-4-13-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/23b3cdb48e28/iovs-63-4-13-f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/ded1c32fe604/iovs-63-4-13-f006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/9e5a6b36c919/iovs-63-4-13-f007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f84/9034715/02b836f1cc04/iovs-63-4-13-f008.jpg

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