Fasnacht Jael S, Wueest Alexandra S, Berres Manfred, Thomann Alessandra E, Krumm Sabine, Gutbrod Klemens, Steiner Luzius A, Goettel Nicolai, Monsch Andreas U
From the Memory Clinic, University Department of Geriatric Medicine FELIX PLATTER, Basel, Switzerland.
Department of Anesthesiology, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, Switzerland.
J Am Geriatr Soc. 2023 Mar;71(3):869-879. doi: 10.1111/jgs.18124. Epub 2022 Nov 8.
Early and accurate detection of cognitive changes using simple tools is essential for an appropriate referral to a more detailed neurocognitive assessment and for the implementation of therapeutic strategies. The Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) are two commonly used psychometric tests for cognitive screening. Both tests have different strengths and weaknesses. Preferences regarding test selection may therefore differ among clinicians. The aim of this retrospective observational cohort study was to define corresponding scores for the MMSE and the MoCA.
We examined the relationship between the cognitive screening tests in 803 German-speaking Memory Clinic outpatients, encompassing a wide range of neurocognitive disorders. We produced a conversion table using the equipercentile equating method with log-linear smoothing. In addition, we conducted a systematic review of existing MMSE-MoCA conversions to create a table allowing for the conversion of MoCA scores into MMSE scores and vice versa using the weighted mean method.
The Memory Clinic sample showed that the prediction of MMSE to MoCA was overall less accurate compared to the conversion from MoCA to MMSE. The 19 studies included after thorough literature search showed that MoCA scores were consistently lower than MMSE scores. Eleven of 19 conversion studies had addressed the conversion of the MoCA to the MMSE, while two studies converted MMSE to MoCA scores. Another six studies applied bi-directional conversions. We provide an easy-to-use table covering the entire range of scores and taking into account all currently existing conversion formulas.
The comprehensive MMSE-MoCA conversion table enables a direct comparison of cognitive test scores at screening examinations and over the course of disease in patients with neurocognitive disorders.
使用简单工具早期准确检测认知变化对于适当转诊进行更详细的神经认知评估以及实施治疗策略至关重要。简易精神状态检查表（MMSE）和蒙特利尔认知评估量表（MoCA）是两种常用的认知筛查心理测量测试。这两种测试都有不同的优缺点。因此，临床医生在测试选择上的偏好可能不同。这项回顾性观察队列研究的目的是确定MMSE和MoCA的相应分数。
我们检查了803名德语区记忆门诊患者的认知筛查测试之间的关系，这些患者涵盖了广泛的神经认知障碍。我们使用具有对数线性平滑的等百分位等值法制作了一个转换表。此外，我们对现有的MMSE-MoCA转换进行了系统评价，以创建一个表格，允许使用加权平均法将MoCA分数转换为MMSE分数，反之亦然。
记忆门诊样本显示，与从MoCA转换为MMSE相比，MMSE对MoCA的预测总体上不太准确。经过全面文献检索后纳入的19项研究表明，MoCA分数始终低于MMSE分数。19项转换研究中有11项涉及从MoCA到MMSE的转换，而两项研究将MMSE转换为MoCA分数。另外六项研究应用了双向转换。我们提供了一个易于使用的表格，涵盖了整个分数范围，并考虑了所有现有的转换公式。
全面的MMSE-MoCA转换表能够在筛查检查时以及神经认知障碍患者的疾病过程中直接比较认知测试分数。
