Peralta Miguel, Dias Carlos Matias, Marques Adilson, Henriques-Neto Duarte, Sousa-Uva Mafalda
CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal; ISAMB, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
CISP, Escola Nacional de Saúde Pública, Universidade Nova de Lisboa, Lisbon, Portugal; Departamento de Epidemiologia, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, Portugal.
Exp Gerontol. 2023 Jan;171:112014. doi: 10.1016/j.exger.2022.112014. Epub 2022 Nov 5.
Few multi-country European studies have investigated the association between grip strength and heart diseases incidence. Thus, the aim of this study is to analyse the longitudinal relationship between grip strength and the diagnosis of heart diseases in European middle-aged and older adults.
A prospective cohort study was conducted using data from the Survey of Health, Aging and Retirement in Europe (2004-2017). Participants were 20,829 middle-aged and older adults from 12 countries. GS was objectively measured by a dynamometer and heart diseases diagnosis was self-reported. Incidence rate of heart diseases was calculated and a Cox proportional hazard regression was performed.
The heart diseases incidence rate decreased from 930 per 100,000 person-years in the lowest quartile to 380 per 100,000 person-years in the highest grip strength quartile. During the 13 years of follow-up, compared to being in the lowest grip strength quartile, being in the highest quartile decreased the hazard of being diagnosed with a heart disease in 36 % (95 % confidence interval [CI]: 0.53, 0.78) for the whole sample, 35 % (95 % CI: 0.51, 0.84) for men and 46 % (95 % CI: 0.40, 0.73) for women.
Grip strength seems to be inversely associated with the incidence of heart diseases among European middle-aged and older adults. Scientific evidence has highlighted the potential role of grip strength as a risk stratifying measure for heart diseases, suggesting its potential to be included in the cardiovascular risk scores used in primary care. However, further research is still needed to clarify it.
很少有欧洲多国研究调查握力与心脏病发病率之间的关联。因此，本研究旨在分析欧洲中老年人握力与心脏病诊断之间的纵向关系。
使用欧洲健康、衰老和退休调查（2004 - 2017年）的数据进行前瞻性队列研究。参与者为来自12个国家的20,829名中老年人。通过测力计客观测量握力，心脏病诊断为自我报告。计算心脏病发病率并进行Cox比例风险回归分析。
心脏病发病率从握力最低四分位数组的每10万人年930例降至握力最高四分位数组的每10万人年380例。在13年的随访期间，与处于握力最低四分位数组相比，处于最高四分位数组使全样本患心脏病的风险降低36%（95%置信区间[CI]：0.53，0.78），男性降低35%（95%CI：0.51，0.84），女性降低46%（95%CI：0.40，0.73）。
握力似乎与欧洲中老年人的心脏病发病率呈负相关。科学证据凸显了握力作为心脏病风险分层指标的潜在作用，表明其有可能纳入初级保健中使用的心血管风险评分。然而，仍需进一步研究加以明确。
