Trauma Medical Center, Department of Orthopedics, West China Hospital of Sichuan University, Chengdu, China.
Department of Orthopedics, The Affiliated Hospital of Weifang Medical University, Weifang, China.
Arch Orthop Trauma Surg. 2023 Jul;143(7):3985-3995. doi: 10.1007/s00402-022-04676-y. Epub 2022 Nov 8.
This study determined independent predictors and developed a predictive nomogram for failed correction of intertrochanteric fractures due to cut-out of the proximal femur nail anti-rotation (PFNA) device.
Demographic and radiological data of 592 adult patients with intertrochanteric fractures (AO 31A) treated by PFNA were collected retrospectively. Independent predictors of cut-out were obtained through univariate and multivariate analyses, and a predictive nomogram was established. The discrimination, calibration, and clinical utility of the nomogram were based on receiver operating characteristic curve (AUC), concordance index (C-index), calibration curve, and decision curve analysis, respectively.
Overall, 18 (3.04%) cases of cut-out occurred. Independent predictors according to the multivariate analysis were body mass index (BMI), poor-to-acceptable quality of reduction, PFNA blade position, and tip-apex distance (TAD). AUC of the nomogram was 0.849, and C-index was 0.849 (95% CI [0.844-0.854]). Bootstrapping yielded a corrected C-index of 0.849. The calibration and decision curves indicated good agreement and clinical benefit of the nomogram.
A reliable predictive nomogram was developed for cut-out of the PFNA in intertrochanteric fractures, based on BMI, quality of reduction, blade position, and TAD.
本研究旨在确定股骨近端防旋髓内钉(PFNA)装置切出导致股骨转子间骨折内固定失败的独立预测因素,并建立预测列线图。
回顾性收集 592 例采用 PFNA 治疗的成人股骨转子间骨折(AO 31A)患者的人口统计学和影像学资料。通过单因素和多因素分析获得切出的独立预测因素,并建立预测列线图。通过接受者操作特征曲线(AUC)、一致性指数(C 指数)、校准曲线和决策曲线分析,分别评估列线图的判别能力、校准能力和临床实用性。
总体而言,18 例(3.04%)发生切出。多因素分析的独立预测因素为体重指数(BMI)、复位质量差/可接受、PFNA 刀片位置和尖端顶点距离(TAD)。列线图的 AUC 为 0.849,C 指数为 0.849(95%CI [0.844-0.854])。Bootstrap 校正后的 C 指数为 0.849。校准和决策曲线表明该列线图具有良好的一致性和临床获益。
基于 BMI、复位质量、刀片位置和 TAD,本研究建立了一种可靠的预测股骨转子间骨折 PFNA 切出的列线图。