University of Pennsylvania, Philadelphia, PA, USA.
Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Trials. 2022 Nov 8;23(1):927. doi: 10.1186/s13063-022-06804-w.
The coronavirus disease 2019 (COVID-19) pandemic resulted in severe interruptions to clinical research worldwide. This global public health crisis required investigators and researchers to rapidly develop and implement new strategies and solutions to mitigate its negative impact on the progress of clinical trials. In this paper, we describe the challenges, strategies, and lessons learned regarding the continuation of a supportive oncology clinical trial during the pandemic. We hope to provide insight into the implementation of clinical trials during a public health emergency to be better prepared for future instances.Trial registration: ClinicalTrials.gov, a service of the US National Institute of Health (NCT03030859). Registered on 22 January 2017.
2019 年冠状病毒病（COVID-19）大流行导致全球临床研究严重中断。这场全球公共卫生危机要求调查人员和研究人员迅速制定和实施新的策略和解决方案，以减轻其对临床试验进展的负面影响。在本文中，我们描述了在大流行期间继续进行支持性肿瘤学临床试验所面临的挑战、策略和经验教训。我们希望为实施临床试验提供一些见解公共卫生紧急情况，以便为未来的情况做好更好的准备。试验注册：ClinicalTrials.gov，美国国立卫生研究院（NCT03030859）的一项服务。于 2017 年 1 月 22 日注册。
