Carlini Sara V, Weiss Sandra J, Mordukhaev Lauren, Jacob Sunu, Flynn Heather A, Deligiannidis Kristina M
Department of Psychiatry, Maimonides Medical Center, Brooklyn, NY, 11219, USA.
Department of Community Health Systems, University of California, San Francisco, CA, 94143, USA.
Biopsychosoc Med. 2022 Nov 8;16(1):23. doi: 10.1186/s13030-022-00252-3.
Prevalence of premenstrual syndrome (PMS) may be as high as 13-18%, but it remains under-recognized and is associated with increased suicidal ideation (SI), plans, and attempts in epidemiological studies. The present study reports on women endorsing premenstrual SI (PMSI) and characterizes this at-risk group and its clinical correlates.
A cross-sectional study assessed demographics, anxiety and depression severity, psychiatric diagnoses, menstrual symptoms, SI, and trauma in adult women at a major medical center over 11 months.
Three hundred two women were assessed. Of 153 participants endorsing premenstrual symptoms, 41 (27%) reported new or worsening concurrent premenstrual passive or active SI. Women who reported PMSI were significantly more likely to be single, unemployed, and childless as well as significantly more likely to report interference from premenstrual symptoms, histories of psychiatric hospitalization, adverse childhood events, suicide attempts, and current and past depression and anxiety compared to women without PMSI. The final regression model indicated the most significant predictors of PMSI were history of a depression diagnosis, severity of current depressive symptoms, and having experienced 3 or more childhood adverse events.
Nearly one-third of women reporting premenstrual symptoms endorsed concurrent SI, a clinically valuable demonstration of the importance of this predictable cyclic risk factor.
经前综合征（PMS）的患病率可能高达13%-18%，但仍未得到充分认识，且在流行病学研究中与自杀意念（SI）、计划和企图的增加有关。本研究报告了认可经前SI（PMSI）的女性情况，并对这一高危群体及其临床相关因素进行了特征描述。
一项横断面研究在一家大型医疗中心对成年女性进行了为期11个月的评估，内容包括人口统计学、焦虑和抑郁严重程度、精神疾病诊断、月经症状、SI和创伤情况。
共评估了302名女性。在153名认可经前症状的参与者中，41名（27%）报告出现新的或加重的经前被动或主动SI。与无PMSI的女性相比，报告有PMSI的女性更有可能单身、失业且无子女，也更有可能报告经前症状的干扰、精神科住院史、儿童期不良事件、自杀未遂以及当前和过去的抑郁与焦虑情况。最终回归模型表明，PMSI的最显著预测因素是抑郁症诊断史、当前抑郁症状的严重程度以及经历过3次或更多次儿童期不良事件。
报告有经前症状的女性中，近三分之一认可同时存在SI，这一具有临床价值的现象证明了这种可预测的周期性风险因素的重要性。
