Wang L L, Liang X, Jia K J, He Y P
The Third Worker's Hospital of Baotou Steel Group, Baotou 014010, China.
Ordos Dongsheng District Hospital, Ordos 017000, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2022 Oct 20;40(10):761-764. doi: 10.3760/cma.j.cn121094-20211229-00638.
To study the pathological types of lung cancer caused by coke oven emissions and analyze the correlation between different exposure levels. In October 2020, the relevant data of 86 confirmed cases of lung cancer caused by coke oven emissions (including basic information of patients, relevant occupational exposure and clinical data) were collected, The workers were grouped according to the different COEs concentrations in their posts: workers in auxiliary posts were taken as the low exposure group (11 persons) , The workers at coke side and furnace bottom are the medium exposure group (14 persons) , and the workers at furnace top are the high exposure group (61 persons) , and the correlation between pathological types of lung cancer and different exposure levels was analyzed. There was no significant difference in age and length of service among the groups (>0.05) ; The number of lung cancer cases and pathological types among workers in each group were statistically significant (=0.044) . After adjusting for interference factors, the number of undifferentiated cancers (mainly small cell lung cancer) increased with the increase of exposure level, with a statistically significant difference (=0.001) . The incidence of lung cancer increased gradually with the length of service, and the incidence rate of lung cancer among workers of different working ages was statistically significant (<0.05) . Undifferentiated small cell carcinoma is the most common pathological type of lung cancer caused by coke oven emissions, and the incidence of lung cancer tends to increase with the length of service.
研究焦炉排放所致肺癌的病理类型，分析不同暴露水平之间的相关性。2020年10月，收集86例焦炉排放所致肺癌确诊病例的相关资料（包括患者基本信息、相关职业暴露及临床资料），根据岗位不同的焦炉逸散物（COEs）浓度对工人进行分组：辅助岗位工人作为低暴露组（11人），焦侧和炉底工人为中等暴露组（14人），炉顶工人为高暴露组（61人），分析肺癌病理类型与不同暴露水平之间的相关性。各组间年龄和工龄差异无统计学意义（>0.05）；各组工人肺癌病例数及病理类型差异有统计学意义（=0.044）。校正干扰因素后，未分化癌（主要为小细胞肺癌）数量随暴露水平升高而增加，差异有统计学意义（=0.001）。肺癌发病率随工龄逐渐升高，不同工龄工人的肺癌发病率差异有统计学意义（<0.05）。未分化小细胞癌是焦炉排放所致肺癌最常见的病理类型，且肺癌发病率有随工龄升高的趋势。
