Zerbo Šporin Dorjana, Domjanič David, Žvanut Boštjan
University of Primorska, Faculty of Health Sciences, Polje 42, 6310 Izola, Slovenia.
Community Health Center Logatec, Notranjska cesta 2, 1370 Logatec, Slovenia.
Zdr Varst. 2022 Sep 28;61(4):231-241. doi: 10.2478/sjph-2022-0031. eCollection 2022 Dec.
The application of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) improves functional capacity and health-related quality of life (HRQoL) at all stages of disease severity. The aim of this study was to determine the effects of PR, performed through exercise training (PR-ET), on functional capacity and HRQoL in patients with stable COPD.
The meta-analysis was performed by including randomized controlled trials (RCTs) involving patients with stable COPD who participated in different types of PR-ET in which six-minute walk distance (6MWD) and/ or St. George's Respiratory Questionnaire total scores (SGRQ) were measured. The data search was conducted in December 2020 and January 2021.
The first meta-analysis showed a statistically significant positive effect (MD=31.73m; p<0.00001) of PR-ET on 6MWD. Similarly, the second meta-analysis found a statistically significant favourable effect of pulmonary rehabilitation through exercise training on SGRQ total scores (MD=-8.09; p=0.002).
PR, which includes several different types of exercise training, has a positive effect on the functional capacity and HRQoL of patients with stable COPD. Further studies should be conducted to determine the effects of home-based PR-ET and PR-ET >8 weeks on SGRQ total scores.
肺康复（PR）在慢性阻塞性肺疾病（COPD）中的应用可在疾病严重程度的各个阶段改善功能能力和健康相关生活质量（HRQoL）。本研究的目的是确定通过运动训练进行的肺康复（PR-ET）对稳定期COPD患者功能能力和HRQoL的影响。
通过纳入涉及稳定期COPD患者的随机对照试验（RCT）进行荟萃分析，这些患者参与了不同类型的PR-ET，其中测量了六分钟步行距离（6MWD）和/或圣乔治呼吸问卷总分（SGRQ）。数据检索于2020年12月和2021年1月进行。
第一项荟萃分析显示PR-ET对6MWD有统计学上显著的积极影响（MD = 31.73m；p < 0.00001）。同样，第二项荟萃分析发现通过运动训练进行的肺康复对SGRQ总分有统计学上显著的有利影响（MD = -8.09；p = 0.002）。
包括几种不同类型运动训练的PR对稳定期COPD患者的功能能力和HRQoL有积极影响。应进行进一步研究以确定家庭式PR-ET和>8周的PR-ET对SGRQ总分的影响。
