Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brazil.
Universidade de São Paulo, Escola de Enfermagem de Ribeirão Preto, PAHO/WHO Collaborating Centre for Nursing Research Development, Ribeirão Preto, SP, Brazil.
Rev Lat Am Enfermagem. 2022 Nov 7;30(spe):e3717. doi: 10.1590/1518-8345.6245.3717. eCollection 2022.
to document adolescents' understanding of chemotherapy-related core adverse events from the Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events and thus begin the validation process of this tool's items with Brazilian adolescents.
this is a prospective, qualitative study of concept elicitation. The participants were 17 adolescents aged 13-18 years and undergoing chemotherapy in three hospitals in São Paulo - SP, Brazil. Cognitive interviews were conducted with questions based on chemotherapy-related adverse events. Data were analyzed for responsiveness and missingness.
adolescents could and were willing to provide descriptive information about their chemotherapy adverse events, including physical and emotional events. Some participants suggested alternative terms to name the adverse events and some used more complex terms, but most were satisfied with the primary terms used by the researchers.
this study represents the first steps towards understanding how adolescent cancer patients identify, name, and describe these events by cognitive interviewing to help design future assessment instruments focused on this age group.
(1) Adolescents' voice is a priority in reporting chemotherapy-related adverse events. (2) Adverse events (AEs) inquiry may best be initiated with open-ended questions. (3) Elicitation studies can include the voices of the target population. (4) Adolescents with cancer can self-report clinically relevant chemotherapy AEs.
从儿科患者报告结局版通用不良事件术语标准中记录青少年对化疗相关核心不良事件的理解，从而开始对该工具项目进行巴西青少年验证。
这是一项前瞻性、定性的概念发掘研究。参与者为来自巴西圣保罗州 3 家医院的 17 名年龄在 13-18 岁之间正在接受化疗的青少年。认知访谈采用基于化疗相关不良事件的问题进行。对反应性和缺失数据进行分析。
青少年能够并愿意提供关于他们化疗不良事件的描述性信息，包括身体和情绪事件。一些参与者建议使用替代术语来命名这些不良事件，而一些人使用了更复杂的术语，但大多数人对研究人员使用的主要术语表示满意。
本研究代表着通过认知访谈了解青少年癌症患者如何识别、命名和描述这些事件的第一步，旨在帮助设计未来关注该年龄组的评估工具。
（1）青少年的声音在报告化疗相关不良事件中至关重要。（2）不良事件（AE）查询最好通过开放式问题开始。（3）启发式研究可以包括目标人群的声音。（4）患有癌症的青少年可以自行报告临床相关的化疗不良事件。
