Department of Clinical and Experimental Sciences, 2a Medicina-ASST Spedali Civili Brescia, University of Brescia, 25100, Brescia, Italy.
High Blood Press Cardiovasc Prev. 2022 Nov;29(6):585-593. doi: 10.1007/s40292-022-00548-z. Epub 2022 Nov 10.
Arterial hypertension represents an important risk factor for the development of cardiac, vascular and renal events, predisposing to heart failure, acute coronary syndromes, peripheral artery disease, stroke, and chronic renal disease. Arterial hypertension leads to the development of subclinical hypertension mediated organ damage (HMOD) which has prognostic relevance and may influence the choice of treatment options. Alterations of cardiac structure and function represent the more widely assessed form of HMOD. This manuscript will focus on the diagnostic opportunities, prognostic significance and treatment of diastolic dysfunction alterations.
动脉高血压是引发心脏、血管和肾脏疾病的重要危险因素，易导致心力衰竭、急性冠状动脉综合征、外周动脉疾病、中风和慢性肾病。动脉高血压会导致亚临床高血压介导的器官损伤（HMOD），具有预后意义，并可能影响治疗方案的选择。心脏结构和功能的改变是评估 HMOD 的更为广泛的形式。本文将重点介绍舒张功能障碍改变的诊断机会、预后意义和治疗。
