King's College London, London, UK.
Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Trials. 2022 Nov 9;23(1):935. doi: 10.1186/s13063-022-06830-8.
Anxiety and depression are increasingly prevalent in adolescents, often causing daily distress and negative long-term outcomes. Despite the significant and growing burden, less than 25% of those with probable diagnosis of anxiety and depression are receiving help in England. Significant barriers to help-seeking exist in this population, with a scarcity of easily accessible, effective, and cost-effective interventions tailored specially for this age group. One intervention that has been shown to be feasible to deliver and with the promise of reducing stress in this age group is a school-based stress workshop programme for 16-18-year-olds (herein called DISCOVER). The next step is to rigorously assess the effectiveness, and cost-effectiveness, of the DISCOVER intervention in a fully powered cluster randomised controlled trial (cRCT). If found to be clinically and cost-effective, DISCOVER could be scaled up as a service model UK-wide and have a meaningful impact on the mental health of adolescents across the country.Trial registration: ISRCTN registry ISRCTN90912799. Registered with ISRCTN 28 May 2020.
焦虑症和抑郁症在青少年中越来越普遍,常常导致他们每天都感到痛苦,并产生负面的长期后果。尽管负担巨大且日益加重,但在英国,接受可能的焦虑和抑郁诊断的人中,不到 25%的人得到了帮助。在这个人群中,存在着寻求帮助的巨大障碍,缺乏专门针对这个年龄段的、容易获得的、有效的和具有成本效益的干预措施。已经有研究表明,一种针对 16-18 岁青少年的基于学校的压力工作坊方案(简称 DISCOVER)是可行的,并且有可能减轻这个年龄段的压力。下一步是在一项充分有力的整群随机对照试验(cRCT)中严格评估 DISCOVER 干预措施的有效性和成本效益。如果发现该方案在临床上有效且具有成本效益,那么 DISCOVER 可以在英国扩大为一种服务模式,对全国青少年的心理健康产生有意义的影响。试验注册:ISRCTN 注册处 ISRCTN85636636。于 2020 年 5 月 28 日在 ISRCTN 注册。