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感染性肺大疱病因:一例报告。

Infected lung bulla caused by : A case report.

作者信息

Moriya Tetsuji, Ohsumi Akihiro, Tanizawa Kiminobu, Matsumura Yasufumi, Date Hiroshi

机构信息

Department of Thoracic Surgery, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Department of Respiratory Medicine, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

出版信息

Respir Med Case Rep. 2022 Oct 31;40:101758. doi: 10.1016/j.rmcr.2022.101758. eCollection 2022.

Abstract

is a rod-shaped, Gram-negative, aerobic bacterium that is part of the normal oral bacterial flora. Although previously considered a non- or low-pathogenic organism, the development of bacterial detection methods has resulted in increased reports of infections such that it has recently been recognized as a causative agent of serious infections even in non-immune-compromised patients. A 77-year-old man with rheumatoid arthritis-associated interstitial lung disease, chronic obstructive pulmonary disease, and diabetes mellitus was diagnosed with a nodule in the left lower lobe of his lung. Thoracoscopic wedge resection was performed, and pus was discharged from the specimen. Mass spectrometry of the swab culture revealed . The patient's postoperative course was uneventful, and he was doing well without recurrence at 13 months after surgery. Since is an oral bacterial flora, the patient consulted a local dentist, and decayed teeth were extracted. Most of the reported cases of serious infections have described infective endocarditis. This is the first report of infected lung bulla due to infection which demonstrates a new pathogenicity.

摘要

是一种杆状、革兰氏阴性需氧菌,是正常口腔细菌菌群的一部分。尽管以前被认为是一种非致病性或低致病性微生物,但细菌检测方法的发展导致关于感染的报告增多,以至于最近它甚至被认为是导致非免疫功能低下患者严重感染的病原体。一名患有类风湿性关节炎相关间质性肺病、慢性阻塞性肺疾病和糖尿病的77岁男性被诊断出左肺下叶有一个结节。进行了胸腔镜楔形切除术,标本中有脓液排出。拭子培养的质谱分析显示……患者术后病程平稳,术后13个月情况良好,无复发。由于……是口腔细菌菌群,患者咨询了当地牙医并拔除了龋齿。大多数报告的严重……感染病例描述的是感染性心内膜炎。这是首例因……感染导致肺大疱感染的报告,显示了一种新的致病性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f893/9637803/c01761c36869/gr1.jpg

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